1428324-89-3

Basic information

• Product Name: C₁₇H₁₆N₂O₃
• Synonyms: C₁₇H₁₆N₂O₃
• CAS NO: 1428324-89-3
• Molecular Weight: 296.326
• Mol File: 1428324-89-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₆N₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₆N₂O₃(1428324-89-3)
• EPA Substance Registry System: C₁₇H₁₆N₂O₃(1428324-89-3)

Safety Data

• Hazardous Substances Data: 1428324-89-3(Hazardous Substances Data)

Upstream product

• 100-83-4 meta-hydroxybenzaldehyde 
• 99-93-4 4-Hydroxyacetophenone 
• 3654-50-0 3-(3-hydroxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one 
• 64-19-7 acetic acid 

Relevant articles and documents

Design and synthesis of 3,5-diaryl-4,5-dihydro-1H-pyrazoles as new tyrosinase inhibitors

In this study, twenty 3,5-diaryl-4,5-dihydro-1H-pyrazole derivatives with hydroxyl(s) (1a-1p, 2a-2d) were synthesized and their inhibitory activity on mushroom tyrosinase was examined. The results showed that among these compounds, 1-(5-(3,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl) ethanone 1d was found to be the most potent tyrosinase inhibitor with IC 50 value of 0.301 μM. Kinetic study revealed that these compounds were competitive inhibitors of tyrosinase and their structure-activity relationships were investigated in this article.