142841-60-9

Usage

Chemical class

Alpha amino acid esters 1-Pyrrolidinecarboxylic acid, 2-butyl-5-(4-hydroxyheptyl)-, phenylmethyl ester belongs to a class of organic compounds that are derived from alpha amino acids by esterification.

Ester derivative

Pyrrolidinecarboxylic acid, 2-butyl-5-(4-hydroxyheptyl), and phenylmethyl The compound is formed by the esterification of pyrrolidinecarboxylic acid with 2-butyl-5-(4-hydroxyheptyl) and phenylmethyl groups.

Potential pharmaceutical applications

Biological activity The compound has potential biological activity, making it a candidate for further research and development in the creation of new drugs.

Industrial applications

Production of cosmetics or fragrances Due to its unique structure and properties, the compound may have potential uses in the production of cosmetics and fragrances.

Structure

A combination of pyrrolidine, butyl, hydroxyheptyl, and phenylmethyl groups The compound's structure consists of a pyrrolidine ring, a butyl chain, a hydroxyheptyl group, and a phenylmethyl ester group, which contribute to its unique properties and potential applications.

Upstream product

• 927-77-5 n-propylmagnesium bromide 
• 142841-56-3 (2R,5R)-N-<(benzyloxy)carbonyl>-5-butyl-2-(4-oxobutyl)pyrrolidine 
• 925-90-6 ethylmagnesium bromide 
• 214072-11-4 (2R,5R)-1-[(Benzyloxy)carbonyl]-2-butyl-5-(4,5-epoxypentyl)pyrrolidine 
• 54313-25-6 4-penten-1-yllithium 
• 5211-23-4 N-carbobenzyloxy-L-proline methyl ester 
• 214072-10-3 (5S)-2-Methoxy-1-[(benzyloxy)carbonyl]-5-methoxycarbonylpyrrolidine 
• 1119-51-3 bromopentene 
• 158149-94-1 (2S,5S)-1-[(Benzyloxy)carbonyl]-2-hydroxymethyl-5-(pent-4-enyl)pyrrolidine 
• 158250-28-3 (2R,5R)-1-[(Benzyloxy)carbonyl]-2-butyl-5-(pent-4-enyl)pyrrolidine 
• 158149-95-2 (2S,5R)-1-[(Benzyloxy)carbonyl]-2-methoxycarbonyl-5-(pent-4-enyl)pyrrolidine 
• 158149-93-0 (2S,5S)-1-[(Benzyloxy)carbonyl]-2-tosyloxymethyl-5-(pent-4-enyl)pyrrolidine 
• 134822-25-6 (2R,5R)-2-<4-(benzoyloxy)butyl>-5-<4-(benzyloxy)butyl>pyrrolidine 
• 134822-20-1 (5S,8S)-1-(benzoyloxy)-12-(benzyloxy)-5,8-dodecanediol 

Downstream Products

• 142841-61-0 (2R,5R)-N-<(benzyloxy)carbonyl>-5-butyl-2-(4-oxoheptyl)pyrrolidine 
• 67217-85-0 (-)-indolizidine 223AB 
• 943979-38-2 (3R,5S,8aR)-3-butyl-5-propyloctahydroindolidine 

Relevant academic research and scientific papers

Synthesis of indolizidines (-)-195B, (-)-223AB and (-)-239AB: (2S,5R)- l-[(benzyloxy)carbonyl]-2-methoxycarbonyl-5-(4pentenyl)pyrrolidine as a versatile chiral building block

The total syntheses of three levogyre 3,5-disubstituted indolizidines, (-)-195B, (-)-223AB and (-)-239AB are described. The employed strategy is based on the utilization of the common enantiopure trans 2,5-disubstituted pyrrolidine 3, which is assembled b

General Entry to the 3,5-Disubstituted Indolizidine Class of Dendrobatid Alkaloids. Total Syntheses of Both Enantiomers of Indolizidines 195B, 223AB, 239AB, and 239CD from a Common Chiral Synthon

A general protocol for the total syntheses of both enantiomers of dendrobatid alkaloids, indolizidines 195B, 223AB, 239AB, and 239CD, belonging to the 3,5-disubstituted indolizidine subclass is described, in which 3,4-dideoxy-D-threo-hexitol (8) has been used as single and common chiral synthon.The syntheses of the (+)- and (-)-enantiomers of these alkaloids begin with (S,S)- and (R,R)-1,2:5,6-diepoxyhexanes (7), respectively, both of which were derived from 8 in three steps and are carried out by way of pyrrolidine formation via the cyclic sulfates leading to the(2R,5R)- and (2S,5S)-trans-2,5-dialkylated pyrrolidines, which were converted to the (+)- and (-)-enantiomers, respectively, of the title indolizidine alkaloids.These syntheses involve the first chiral preparations of indolizidines 239AB, 239CD both in natural (-)- and unnatural (+)-enantiomeric forms, which confirm the absolute configurations of natural 239AB and 239CD as 3R,5S,8aR and 3R,5R,8aR, respectively.