158149-94-1

Basic information

• Product Name: (2S,5S)-1-[(Benzyloxy)carbonyl]-2-hydroxymethyl-5-(pent-4-enyl)pyrrolidine
• Synonyms: (2S,5S)-1-[(Benzyloxy)carbonyl]-2-hydroxymethyl-5-(pent-4-enyl)pyrrolidine
• CAS NO: 158149-94-1
• Molecular Weight: 303.401
• Mol File: 158149-94-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S,5S)-1-[(Benzyloxy)carbonyl]-2-hydroxymethyl-5-(pent-4-enyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5S)-1-[(Benzyloxy)carbonyl]-2-hydroxymethyl-5-(pent-4-enyl)pyrrolidine(158149-94-1)
• EPA Substance Registry System: (2S,5S)-1-[(Benzyloxy)carbonyl]-2-hydroxymethyl-5-(pent-4-enyl)pyrrolidine(158149-94-1)

Safety Data

• Hazardous Substances Data: 158149-94-1(Hazardous Substances Data)

Upstream product

• 158149-95-2 (2S,5R)-1-[(Benzyloxy)carbonyl]-2-methoxycarbonyl-5-(pent-4-enyl)pyrrolidine 
• 54313-25-6 4-penten-1-yllithium 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 147-85-3 L-proline 
• 501-53-1 benzyl chloroformate 
• 1119-51-3 bromopentene 
• 214072-10-3 (5S)-2-Methoxy-1-[(benzyloxy)carbonyl]-5-methoxycarbonylpyrrolidine 
• 5211-23-4 N-carbobenzyloxy-L-proline methyl ester 

Downstream Products

• 179330-88-2 (2S,5R)-2-Acetoxymethyl-5-pent-4-enyl-pyrrolidine-1-carboxylic acid benzyl ester 
• 67217-85-0 (-)-indolizidine 223AB 
• 943979-38-2 (3R,5S,8aR)-3-butyl-5-propyloctahydroindolidine 
• 142925-64-2 (2R,5R)-N-<(benzyloxy)carbonyl>-5-butyl-2-(4-oxopentyl)pyrrolidine 
• 142841-60-9 (2R,5R)-N-<(benzyloxy)carbonyl>-2-(4-hydroxyheptyl)-5-butylpyrrolidine 
• 142841-61-0 (2R,5R)-N-<(benzyloxy)carbonyl>-5-butyl-2-(4-oxoheptyl)pyrrolidine 
• 158250-28-3 (2R,5R)-1-[(Benzyloxy)carbonyl]-2-butyl-5-(pent-4-enyl)pyrrolidine 
• 214072-11-4 (2R,5R)-1-[(Benzyloxy)carbonyl]-2-butyl-5-(4,5-epoxypentyl)pyrrolidine 
• 214072-13-6 (2R,5R)-1-[(Benzyloxy)carbonyl]-2-butyl-5-(4-hydroxyhept-6-enyl)pyrrolidine 
• 214072-14-7 (2R,5R)-1-[(Benzyloxy)carbonyl]-5-butyl-2-(4,7-dihydroxyheptyl)pyrrolidine 
• 214072-16-9 (2R,5R)-1-[(Benzyloxy)carbonyl]-2-butyl-5-(4-hydroxo-7-benzoyloxyheptyl)pyrrolidine 
• 214072-15-8 (2R,5R)-1-[(Benzyloxy)carbonyl]-5-butyl-2-(4-hydroxy-7-benzoyloxyheptyl)pyrrolidine 
• 179330-89-3 (2S,5R)-2-Acetoxymethyl-5-(4-oxo-pentyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 158149-93-0 (2S,5S)-1-[(Benzyloxy)carbonyl]-2-tosyloxymethyl-5-(pent-4-enyl)pyrrolidine 

Relevant articles and documents

Synthesis of indolizidines (-)-195B, (-)-223AB and (-)-239AB: (2S,5R)- l-[(benzyloxy)carbonyl]-2-methoxycarbonyl-5-(4pentenyl)pyrrolidine as a versatile chiral building block

The total syntheses of three levogyre 3,5-disubstituted indolizidines, (-)-195B, (-)-223AB and (-)-239AB are described. The employed strategy is based on the utilization of the common enantiopure trans 2,5-disubstituted pyrrolidine 3, which is assembled b

A short and highly stereocontrolled total synthesis of (3R,5R,8aR)-3-n-Butyl-5-methylindolizidine

Total synthesis of (-) (3R,5R,8aR)-3-n-Butyl-5-methylindolizidine is described in 9 steps (22% overall yield) from L-proline.