1428876-79-2Relevant academic research and scientific papers
Synthesis, crystal structure and fungicidal activity of novel 1,5-Diaryl-3-benzoyloxy-1H-pyrazoles
Liu, Yuan-Yuan,Li, Yi,Zhu, Hong-Jun,Chen, Kai,Huang, Bin,Yang, Ya-Ping
, p. 4883 - 4886 (2014)
Seven novel 1,5-diaryl-3-benzoyloxy-1H-pyrazoles (2a-2g) were prepared by the DCC condensation of 1,5-diaryl-1H-pyrazol-3-ols (1a- 1g) with benzoic acid. Their structures were characterized by elemental analysis, IR, 1H NMR and mass spectral data. The structure of 5- (3,4-dimethoxyphenyl)-1-phenyl-3-benzoyloxy-1H-pyrazole (2d) was also determined by single crystal X-ray diffraction analysis. Bioassay results indicated that the compounds 5-(4-fluorophenyl)-1-phenyl-3-benzoyloxy-1H-pyrazole (2f) and 1,5-diphenyl-3-benzoyloxy-1Hpyrazole (2a) exhibited excellent-to-medium fungicidal activity against Sclerotinia sclerotiorum at a dosage of 10 ìg/mL. The structureactivity relationships (SAR) were also discussed.
Crystal structures, vibrational spectra, and fungicidal activity of 1,5-diaryl-3-oxypyrazoles
Li, Yi,Liu, Yuanyuan,Xiong, Yihuang,Xiong, Xiaohui
, p. 1302 - 1316 (2014/02/14)
The aryloxypyrazole structure is present in a number of bioactive molecules. Four 1,5-diaryl-3-oxypyrazoles containing benzoyl (I), thiazolidinethione (II and III) or per-O-Acetylated glucopyranosyl (IV) moieties were characterized by single-crystal X-ray
