1429656-37-0Relevant academic research and scientific papers
Iodine-Mediated Electrochemical C(sp2)-H Amination: Switchable Synthesis of Indolines and Indoles
Hu, Kangfei,Zhang, Yan,Zhou, Zhenghong,Yang, Yu,Zha, Zhenggen,Wang, Zhiyong
, p. 5773 - 5777 (2020)
A metal-free electrochemical intramolecular C(sp2)-H amination using iodine as a mediator was developed. This method enables a switchable synthesis of indoline and indole derivatives, respectively, from easily available 2-vinyl anilines.
Iodine-catalyzed diamination of styrene in water with the oxidation of H2O2
Liu, Liyan,Sun, Qi,Yan, Zicong,Liang, Xinping,Zha, Zhenggen,Yang, Yu,Wang, Zhiyong
supporting information, p. 3927 - 3930 (2018/09/11)
An environmentally friendly diamination was developed in the presence of TMDAI/H2O2 with water as the only by-product. A series of 3-Amino indolines can be obtained in good to excellent yields. The reaction conditions are very mild and no any organic solvent or metal was involved in the reaction.
Synthetic route to chiral indolines via ring-opening/C-N cyclization of activated 2-haloarylaziridines
Ghorai, Manas K.,Nanaji
, p. 3867 - 3878 (2013/06/05)
A practical approach for the synthesis of 3-substituted indolines via regio- and stereoselective SN2-type ring-opening of 2-(2-halophenyl)-N-tosylaziridines with heteroatomic nucleophiles (O, N, and S) followed by palladium-catalyzed intramolecular C-N cyclization is reported in excellent yields (up to >99%) and enantiomeric excess (ee 99%).
