142977-70-6

Basic information

• Product Name: methyl 2-cyclohexyl-2,2-difluoroacetate
• Synonyms: methyl 2-cyclohexyl-2,2-difluoroacetate
• CAS NO: 142977-70-6
• Molecular Weight: 192.206
• Mol File: 142977-70-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2-cyclohexyl-2,2-difluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-cyclohexyl-2,2-difluoroacetate(142977-70-6)
• EPA Substance Registry System: methyl 2-cyclohexyl-2,2-difluoroacetate(142977-70-6)

Safety Data

• Hazardous Substances Data: 142977-70-6(Hazardous Substances Data)

Upstream product

• 105398-69-4 Cyclohexanecarboxylic acid 2-thioxo-2H-pyridin-1-yl ester 
• 680-15-9 2,2-difluoro-2-(fluorosulfonyl)acetate 
• 110-83-8 cyclohexene 
• 67-56-1 methanol 
• 142977-55-7 1,1-dichloro-2,2-difluoro-1-(2-pyridylthio)-2-cyclohexylethane 

Relevant articles and documents

Photoredox Catalysis Mediated Application of Methyl Fluorosulfonyldifluoroacetate as the CF2CO2R Radical Source

A new application of trifluoromethylating reagent, methyl fluorosulfonyldifluoroacetate (FO2SCF2CO2Me, Chen's reagent), as the carbomethoxydifluoromethylating reagent under visible light photoredox conditions is reported. The visible-light-induced reaction of FO2SCF2CO2Me with unactivated alkenes, styrenes, or heteroarenes affords a variety of carbomethoxydifluoromethylated products.

α,α-Difluoroalkanecarboxylic acids: A general synthesis via alkyl radical addition to 1,1-dichloro-2,2-difluoroethylene

Photodecomposition of alkanoic acid esters of N-hydroxy-2-thiopyridone with 1,1-dichloro-2,2-difluoroethylene gives alkyl-radical-trapped products, which give α,α-difluoroalkanoic acids and their methyl esters on hydrolytic or methanolytic treatment with silver nitrate.