142992-04-9Relevant academic research and scientific papers
Tandem Zinc Mediated Reductive Cleavage-Reductive Amination as a New Approach to Substituted Pyrrolidines from Homoallylic Amines
Vanucci, Corinne,Brusson, Xavier,Verdel, Valerie,Zana, Frederique,Dhomane, Hamid,Lhommet, Gerard
, p. 2971 - 2974 (1995)
N-Boc or N-Cbz homoallylic amines are converted in four steps into pyrrolidines through a sequence involving as a key-step a tandem zinc mediated reductive amination from an intermediate 1,3-oxazin-2-one
Reductive Cyclization of Carbon-Centered Glycine Radicals; A Novel Synthetic Route to Cyclic α-Amino Acids
Esch, Peter M.,Hiemstra, Henk,Boer, Richard F. de,Speckamp, W. Nico
, p. 4659 - 4676 (2007/10/02)
Reductive cyclizations (tributyltin hydride, AIBN) of several α-(phenylthio)glycine derivatives with a 3-alkenyl substituent at nitrogen are reported.These reactions proceed via 2-aza-5-alken-1-yl radicals as intermediates which bear electron-withdrawing
