Tandem Zinc Mediated Reductive Cleavage-Reductive Amination as a New Approach to Substituted Pyrrolidines from Homoallylic Amines

DOI: 10.1016/0040-4039(95)00354-F

Source and publish data:

Tetrahedron Letters p. 2971 - 2974 (1995)

Update date:2022-07-30

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Authors:

Vanucci, Corinne

Brusson, Xavier

Verdel, Valerie

Zana, Frederique

Dhomane, Hamid

Lhommet, Gerard

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Article abstract of DOI:10.1016/0040-4039(95)00354-F

N-Boc or N-Cbz homoallylic amines are converted in four steps into pyrrolidines through a sequence involving as a key-step a tandem zinc mediated reductive amination from an intermediate 1,3-oxazin-2-one

Full text of DOI:10.1016/0040-4039(95)00354-F

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