143007-99-2Relevant academic research and scientific papers
Visible-light-mediated benzylic sp3 C-H bond functionalization to C-Br or C-N bond
Hou, Tianyuan,Lu, Ping,Li, Pixu
supporting information, p. 2273 - 2276 (2016/05/10)
A visible-light-promoted functionalization of unactivated benzylic sp3 C-H bonds was developed. Ethylbenzene derivatives were converted to the corresponding benzyl bromides or afforded benzylamine derivatives in a one-pot manner under visible light photoredox conditions.
Additions of 1-(α-Aminoalkyl)benzotriazoles to Enol Ethers. New Routes to 1,3-Amino-Ethers
Katritzky, Alan R.,Rachwal, Stanislaw,Rachwal, Bogumila,Steel, Peter J.
, p. 4932 - 4939 (2007/10/02)
1-(α-Aminoalkyl)benzotriazoles add readily to enol ethers to give the corresponding 1-benzotriazolyl-3-aminoalkylethers in high yields.Subsequent replacement of the benzotriazole moiety by an alkyl or aryl group (with a Grignard reagent) or by a hydrogen atom (with lithium aluminum hydride) affords 1,3-amino-ethers in good yields.Anchimeric assistance by the amino groups in the substitutions of the benzotriazolyl moiety facilitates the reactions.Full stereochemistry is assigned to the stereoisomeric products on the basis of NMR techniques and X-ray diffraction.
