1430211-17-8

Basic information

• Product Name: 5-(2-((5-(2-(3,4-dimethoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-yl)thio)ethoxy)-1H-indazole
• CAS NO: 1430211-17-8
• Molecular Weight: 532.639
• Mol File: 1430211-17-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(2-((5-(2-(3,4-dimethoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-yl)thio)ethoxy)-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-((5-(2-(3,4-dimethoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-yl)thio)ethoxy)-1H-indazole(1430211-17-8)
• EPA Substance Registry System: 5-(2-((5-(2-(3,4-dimethoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-yl)thio)ethoxy)-1H-indazole(1430211-17-8)

Safety Data

• Hazardous Substances Data: 1430211-17-8(Hazardous Substances Data)

Upstream product

• 1430211-86-1 3-(3,4-dimethoxyphenyl)-3-methylbutan-2-ol 
• 717105-57-2 2-(3,4-dimethoxyphenyl)-2-methylpropanal 
• 23023-16-7 2‐(3,4‐dimethoxyphenyl)‐2‐methylpropionitrile 
• 1430211-87-2 1-bromo-3-(3,4-dimethoxyphenyl)-3-methylbutan-2-one 
• 4461-99-8 3-(3,4-dimethoxyphenyl)-3-methylbutan-2-one 

Relevant articles and documents

Discovery of a Potent and Orally Efficacious TGR5 Receptor Agonist

TGR5 is a G protein-coupled receptor (GPCR), activation of which promotes secretion of glucagon-like peptide-1 (GLP-1) and modulates insulin secretion. The 2-thio-imidazole derivative 6g was identified as a novel, potent, and selective TGR5 agonist (hTGR5