1430403-45-4

Basic information

• Product Name: 2-{2-[4-(4-[18F]-fluorobenzyl)piperazin-1-yl]-2-oxoethyl}isoindolin-1-one
• CAS NO: 1430403-45-4
• Molecular Weight: 366.425
• Mol File: 1430403-45-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{2-[4-(4-[18F]-fluorobenzyl)piperazin-1-yl]-2-oxoethyl}isoindolin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{2-[4-(4-[18F]-fluorobenzyl)piperazin-1-yl]-2-oxoethyl}isoindolin-1-one(1430403-45-4)
• EPA Substance Registry System: 2-{2-[4-(4-[18F]-fluorobenzyl)piperazin-1-yl]-2-oxoethyl}isoindolin-1-one(1430403-45-4)

Safety Data

• Hazardous Substances Data: 1430403-45-4(Hazardous Substances Data)

Upstream product

• 39221-42-6 (1-oxo-1,3-dihydro-2H-isoindol-2-yl)carboxylic acid 
• 1279870-20-0 C₁₉H₂₅N₃O₄ 
• 96017-03-7 methyl (1-oxo-1,3-dihydro-2H-isoindol-2-yl)acetate 
• 119-67-5 o-carboxybenzaldehyde 
• 1430403-58-9 2-(2-oxo-2-(piperazin-1-yl)ethyl)isoindolin-1-one trifluoroacetate 
• 115109-21-2 4-[18F]fluorobenzaldehyde 
• 100-10-7 4-dimethylamino-benzaldehyde 

Relevant articles and documents

Synthesis and radiosynthesis of a novel PET fluorobenzyl piperazine for melanoma tumour imaging; [18F]MEL054

2-{2-[4-(4-[18F]-Fluorobenzyl)piperazin-1-yl]-2-oxoethyl}isoindolin-1-one ([18F]MEL054), is a new potent indolinone-based melanin binder designed to target melanotic tumours. [18F]MEL054 was prepared by an automated two-step radiosynthesis, comprising of