39221-42-6

Basic information

• Product Name: (1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID
• Synonyms: 2-(1-OXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)ACETIC ACID;(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID;(1-OXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)ACETIC ACID;TIMTEC-BB SBB010845;ISOINDOLIN-1-ONE-2-ACETIC ACID;1,3-Dhydro-1-oxo-2H-isoindole-2-acetic acid;1,3-Dihydro-1-oxo-2H-isoindole-2-aceticacid;2-(1-Oxoisoindolin-2-yl)acetic acid
• CAS NO: 39221-42-6
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.18
• Mol File: 39221-42-6.mol

Chemical Properties

• Melting Point: 208-211 °C
• Boiling Point: 439.8 °C at 760 mmHg
• Flash Point: 219.8 °C
• Appearance: /
• Density: 1.382g/cm³
• Vapor Pressure: 1.65E-08mmHg at 25°C
• Refractive Index: 1.617
• Storage Temp.: 2-8°C
• PKA: 3.61±0.10(Predicted)
• CAS DataBase Reference: (1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID(39221-42-6)
• EPA Substance Registry System: (1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID(39221-42-6)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 39221-42-6(Hazardous Substances Data)

Usage

Uses

Used in Neurological Disorder Treatment:
Caroverine is used as a therapeutic agent for neurological disorders such as tinnitus and vertigo. Its antagonistic action on NMDA receptors helps in managing the symptoms associated with these conditions by modulating the overactivity of these receptors in the central nervous system.
Used in Pain Management:
As an analgesic, caroverine is utilized for its pain-relieving properties. Its interaction with NMDA receptors contributes to the attenuation of pain signals, providing relief in various painful conditions.
Used in Neuroprotection:
Caroverine serves as a neuroprotective agent, safeguarding neurons from damage or degeneration. Its ability to modulate NMDA receptor activity may help in protecting the nervous system from various insults, including those caused by oxidative stress or excitotoxicity.
Used in Combination Therapy:
Caroverine is also investigated for its potential use in combination with other drugs to enhance their therapeutic effects. The synergistic action of caroverine with other medications may improve treatment outcomes in various conditions, particularly in the management of pain and neurological disorders.

InChI:InChI=1/C10H9NO3/c12-9(13)6-11-5-7-3-1-2-4-8(7)10(11)14/h1-4H,5-6H2,(H,12,13)

Upstream product

• 96017-03-7 methyl (1-oxo-1,3-dihydro-2H-isoindol-2-yl)acetate 
• 119-67-5 o-carboxybenzaldehyde 
• 4702-13-0 N-phthaloylglycine 
• 52242-36-1 2,2-diethyl-4H-[1,3,2]oxazaborol-5-one 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 56-40-6 glycine 
• 2417-73-4 methyl 2-bromomethylbenzoate 
• 623-33-6 glycine ethyl ester hydrochloride 

Downstream Products

• 1353053-84-5 {6-[4-(1-boc-piperidin-4-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid methyl ester 
• 1353054-10-0 {6-[4-(1-boc-piperidin-4-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid 
• 1335100-76-9 [1-oxo-6-(4-piperidinium-4-yl-benzoylamino)-1,3-dihydroisoindol-2-yl]acetic acid trifluoroacetate 
• 1430403-45-4 2-{2-[4-(4-[18F]-fluorobenzyl)piperazin-1-yl]-2-oxoethyl}isoindolin-1-one 
• 1430403-62-5 2-{2-[4-(4-fluorobenzyl)piperazin-1-yl]-2-oxoethyl}isoindolin-1-one 
• 1447331-32-9 {6-[4-(4-boc-piperazin-1-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid methyl ester 
• 1447330-19-9 [1-oxo-6-(4-piperazinium-1-yl-benzoylamino)-1,3-dihydroisoindol-2-yl]acetic acid trifluoroacetate 
• 1447331-89-6 {6-[4-(4-boc-piperazin-1-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid 

Relevant articles and documents

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