143097-36-3

Upstream product

• 99-09-2 3-nitro-aniline 
• 143249-12-1 N-(3-nitrophenyl)-S-methylisothiuronium iodide 
• 143097-38-5 2-(3-nitrophenylimino)-1,2,3,4,5,6-hexahydropyrimidine 
• 100-39-0 benzyl bromide 
• 709-72-8 3-nitrophenylthiourea 
• 143097-26-1 2--1,2,3,4-tetrahydropyrimidine 

Relevant academic research and scientific papers

Cyclic guanidines; IV. Intramolecular nucleophilic aromatic substitution of hydrogen in (3-nitrophenyl)guanidines

Cyclization of substituted (3-nitrophenyl)guanidines is achieved in basic medium by nucleophilic displacement of hydrogen. The reaction offers a new route to benzimidazoles as well as to tricyclic imidazo-, pyrimido- and diazepino-benzimidazoles with unco