143097-38-5

Upstream product

• 99-09-2 3-nitro-aniline 
• 709-72-8 3-nitrophenylthiourea 
• 143249-12-1 N-(3-nitrophenyl)-S-methylisothiuronium iodide 
• 109-76-2 Trimethylenediamine 

Downstream Products

• 143097-26-1 2--1,2,3,4-tetrahydropyrimidine 
• 143097-35-2 10-Benzyl-6-nitro-2,3,4,10-tetrahydro-benzo[4,5]imidazo[1,2-a]pyrimidine 
• 143097-36-3 10-benzyl-8-nitro-2,3,4,10-tetrahydropyrimido<1,2-a>benzimidazole 
• 143249-10-9 2--1,2,3,4-tetrahydropyrimidine hydroiodide 

Relevant academic research and scientific papers

Cyclic guanidines; IV. Intramolecular nucleophilic aromatic substitution of hydrogen in (3-nitrophenyl)guanidines

Cyclization of substituted (3-nitrophenyl)guanidines is achieved in basic medium by nucleophilic displacement of hydrogen. The reaction offers a new route to benzimidazoles as well as to tricyclic imidazo-, pyrimido- and diazepino-benzimidazoles with unco