143100-11-2

Upstream product

• 188183-31-5 (2RS)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 3-phenyl-2-cyanopropanoate 
• 106-95-6 allyl bromide 
• 132640-95-0 (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl (E)-2-cyanocinnamate 

Relevant academic research and scientific papers

Asymmetric Synthesis of β-Lactams. Highly Diastereoselective Alkylation of Chiral 2-Cyano Esters

Enolates derived from 10-(dicyclohexylsulfamoyl)isobornyl 2-substituted-2-cyanoacetates were alkylated with very good yield and high diastereoselectivity.The reduction of the resulting reaction products and subsequent cyclization of the β-amino acids led

Chiral 2-Cyanocinnamates in Conjugate Addition Asymmetric Enolate Trapping Reactions

Chiral 2-cyannocinnamates react with L-selectride to give an intermediate enolate which can be stereoselectively trapped with different halides to afford α-substituted phenylalanine precursors with excellent chemical yields and good diastereomeric excess.