188183-31-5

Upstream product

• 132640-95-0 (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl (E)-2-cyanocinnamate 

Downstream Products

• 144631-57-2 (3R)-3-benzyl-3-methyl-2-azetidinone 
• 144631-56-1 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-(aminomethyl)-2-methyl-3-phenylpropanoate 
• 144631-58-3 (2S)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-(aminomethyl)-2-methyl-3-phenylpropanoate 
• 148118-18-7 (R)-2-Aminomethyl-2-benzyl-5-phenyl-pentanoic acid (1S,2R,4R)-1-[(dicyclohexylsulfamoyl)-methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 148118-17-6 (R)-2-Aminomethyl-2-benzyl-5-methyl-hexanoic acid (1S,2R,4R)-1-[(dicyclohexylsulfamoyl)-methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 148118-16-5 (R)-2-Aminomethyl-2-benzyl-4-methyl-pentanoic acid (1S,2R,4R)-1-[(dicyclohexylsulfamoyl)-methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 148118-15-4 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-(aminomethyl)-2-benzylpentanoate 
• 108211-28-5 (R)-(-)-2-cyano-2-methyl-3-phenylpropionic acid 
• 188183-38-2 (2S)-2-benzyl-2-cyano-4-pentenoic acid 
• 143100-10-1 (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl (R)-3-phenyl-2-allyl-2-cyanopropanoate 
• 174061-36-0 (2R)-(1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-amino-2-cyano-3-phenylpropanoate 
• 158149-97-4 (2S)-(1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-amino-2-cyano-3-phenylpropanoate 
• 143100-04-3 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-cyano-2-methyl-3-phenylpropanoate 
• 143100-05-4 (2S)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-cyano-2-methyl-3-phenylpropanoate 

Relevant academic research and scientific papers

Synthesis of (R)- 3-alkyl-3-benzyl-2-azetidinones in enantiomerically pure form

The diastereoselective alkylation of the enolate of 10-dicyclohexylsulfamoylisobornyl 3-phenyl-2-cyanopropanoate is reported. This alkylation took place with very good yield and selectivity and the reaction product was reduced and cyclised to the correspo