Asymmetric Synthesis of β-Lactams. Highly Diastereoselective Alkylation of Chiral 2-Cyano Esters

DOI: 10.1021/jo00088a034

Source and publish data:

Journal of Organic Chemistry p. 2497 - 2505 (1994)

Update date:2022-07-30

Topics:

Authors:

Cativiela, Carlos

Diaz-de-Villegas, Maria D.

Galvez, Jose A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00088a034

Enolates derived from 10-(dicyclohexylsulfamoyl)isobornyl 2-substituted-2-cyanoacetates were alkylated with very good yield and high diastereoselectivity.The reduction of the resulting reaction products and subsequent cyclization of the β-amino acids led

Full text of DOI:10.1021/jo00088a034

Products guided by the article

Product name:(1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl (S)-3-phenyl-2-allyl-2-cyanopropanoate

Cas No:143100-11-2

R&D Labs maybe for 143100-11-2

zonk drug r&d limited

Contact:+86-20-32051076

Address:1105,Building A, International Business Incubator,Science City
Luoyang Aoda chemical Co.,Ltd.

Contact:+86-379-67518785 67516588

Address:MiaoWan industry district,YanShi City,Henan,China
Jingzhou TianHe Sci&Tech Chemical Co., Ltd.

Contact:86-716-8331612

Address:Jiangjin Road, #18, High-grade technology industries development district, Jingzhou city, Hubei province
Chongqing Changfeng Chemical Co., Ltd.

website:http://www.changfengchem.com

Contact:+86-23-67896333

Address:30th Floor, Longhu Ziduxingzuo Building A, 1st Branch,YuSong Rd., Yubei District, Chongqing, China
Zhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd

Contact:+86 411 84674606

Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China

Relevant to this article

Imidazole Schiff base ligands: Synthesis, coordination complexes and biological activities

Doi:10.1016/j.poly.2013.03.023
(2013)
Indole synthesis by conjugate addition of anilines to activated acetylenes and an unusual ligand-free copper(II)-mediated intramolecular cross-coupling

Doi:10.1002/chem.201202307
(2012)
Photochemie der 1-(Carbmethoxy-aryl)- und 1-(Carboxy-aryl)-3-(3-alkyl-benzthiazolinyliden-(2))-triazene als potentielle CEL-Farbstoffe

Doi:10.1002/prac.19923340308
(1992)
Pyrrole-based scaffolds for turn mimics

Doi:10.1021/ol103022m
(2011)
Synthesis of the C4- epi -lomaiviticin B core reveals subtle stereoelectronic effects

Doi:10.1021/ol400832r
(2013)
A New Annulation Based on a One-Pot Double Michael Addition Using Aluminum Tris(2,6-diphenylphenoxide) (ATPH)

Doi:10.1055/s-1997-793
(1997)

Article Doi