143120-72-3Relevant academic research and scientific papers
Diastereoselective alkylation and reduction of β-alkoxyacylsilanes: Stereoselective construction of three contiguous stereogenic centers
Honda, Mitsunori,Ohkura, Naoto,Saisyo, Shin-Ichi,Segi, Masahito,Nakajima, Tadashi
, p. 8203 - 8212 (2003)
The nucleophilic addition reaction to acylsilanes, having stereogenic centers at the α and β positions, derived from the aldol reaction of dimethyl acetals and acylsilane silyl enol ethers gives the corresponding α-silylalcohols in high yields with excellent diastereoselectivity. The protiodesilylation of α-silylalcohols proceeds with complete retention of the configuration. In addition, the reduction of acylsilanes having stereogenic centers at the α and β positions affords the corresponding α-silylalcohols in good yields with high diastereoselectivity similarly to the nucleophilic addition. And the treatment of acylsilanes having a phenyl group on silicon atom with fluoride ion results in the formation of phenyl carbinol derivatives via migration of the phenyl group with high diastereoselectivity.
Addition of 1-(α-Alkoxybenzyl)benzotriazoles to Enol Ethers. New Routes to 1,3-Diethers
Katritzky, Alan R.,Rachwal, Stanislaw,Rachwal, Bogumila,Steel, Peter J.
, p. 4925 - 4931 (2007/10/02)
1-(α-Alkoxybenzyl)benzotriazoles undergo reversible ionization in solution to a benzotriazolyl anion (Bt-) and carboxonium cations PhCH:O+R.These cations can attack the β carbon of enol ethers to give cation adducts which add the Bt
