1431411-28-7

Basic information

• Product Name: N¹-(2-(1-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)ethyl)-N³-ethylisophthalamide
• Synonyms: N¹-(2-(1-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)ethyl)-N³-ethylisophthalamide
• CAS NO: 1431411-28-7
• Molecular Weight: 480.591
• Mol File: 1431411-28-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N¹-(2-(1-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)ethyl)-N³-ethylisophthalamide(CAS DataBase Reference)
• NIST Chemistry Reference: N¹-(2-(1-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)ethyl)-N³-ethylisophthalamide(1431411-28-7)
• EPA Substance Registry System: N¹-(2-(1-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)ethyl)-N³-ethylisophthalamide(1431411-28-7)

Safety Data

• Hazardous Substances Data: 1431411-28-7(Hazardous Substances Data)

Upstream product

• 126926-40-7 methyl 3-(ethylcarbamoyl)benzoate 
• 126926-33-8 m-(ethylaminocarbonyl)benzoic acid 
• 16269-66-2 4-chlorothieno[3,2-d]pyrimidine 
• 875339-14-3 4-chlorothieno[3,2-d]pyrimidine-6-carbonyl chloride 
• 875515-76-7 4-chlorothieno[3,2-d]pyrimidine-6-carboxylic acid 
• 1877-71-0 benzene 1,3-dicarboxylic acid monomethyl ester 
• 1431411-18-5 4-chlorothieno[3,2-d]pyrimidine-6-carboxamide 
• 1431411-20-9 tert-butyl (2-(1-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)ethyl)carbamate 

Relevant articles and documents

THIENO[3,2-D]PYRIMIDINE-6-CARBOXAMIDES AND ANALOGUES AS SIRTUIN MODULATORS

Provided herein are novel substituted thieno[3,2-d]pyrimidine-6-carboxamide sirtuin inhibitors and methods of use thereof. The sirtuin inhibitors may be used for inhibiting a sirtuin-mediated biological process, and, e.g. for treating and/or preventing diseases and disorders including, but not limited to cancer, neurodegenerative disease and inflammation. Also provided herein are pharmaceutical compositions comprising these sirtuin inhibitors and compositions comprising a sirtuin inhibitor in combination with another therapeutic agent.