875515-76-7 Usage
Uses
Used in Pharmaceutical Industry:
4-Chlorothieno[3,2-d]pyrimidine-6-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Chlorothieno[3,2-d]pyrimidine-6-carboxylic acid serves as a precursor for the production of agrochemicals, such as pesticides and herbicides, due to its ability to be incorporated into the molecular structures of these compounds.
Used in Organic Chemistry Research:
4-Chlorothieno[3,2-d]pyrimidine-6-carboxylic acid is utilized as a starting material in organic chemistry for the synthesis of complex molecules. Its unique structure and functional groups make it a valuable component in the development of novel organic compounds with potential applications in various fields.
While the biological activities of 4-Chlorothieno[3,2-d]pyrimidine-6-carboxylic acid are not yet fully understood, ongoing research may reveal its potential in various applications, such as drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 875515-76-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,5,5,1 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 875515-76:
(8*8)+(7*7)+(6*5)+(5*5)+(4*1)+(3*5)+(2*7)+(1*6)=207
207 % 10 = 7
So 875515-76-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H3ClN2O2S/c8-6-5-3(9-2-10-6)1-4(13-5)7(11)12/h1-2H,(H,11,12)
875515-76-7Relevant academic research and scientific papers
THIENO[3,2-D]PYRIMIDINE-6-CARBOXAMIDES AND ANALOGUES AS SIRTUIN MODULATORS
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Page/Page column 63, (2014/09/29)
Provided herein are novel substituted thieno[3,2-d]pyrimidine-6-carboxamide sirtuin inhibitors and methods of use thereof. The sirtuin inhibitors may be used for inhibiting a sirtuin-mediated biological process, and, e.g. for treating and/or preventing diseases and disorders including, but not limited to cancer, neurodegenerative disease and inflammation. Also provided herein are pharmaceutical compositions comprising these sirtuin inhibitors and compositions comprising a sirtuin inhibitor in combination with another therapeutic agent.
Discovery of thieno[3,2-d ]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3
Disch, Jeremy S.,Evindar, Ghotas,Chiu, Cynthia H.,Blum, Charles A.,Dai, Han,Jin, Lei,Schuman, Eli,Lind, Kenneth E.,Belyanskaya, Svetlana L.,Deng, Jianghe,Coppo, Frank,Aquilani, Leah,Graybill, Todd L.,Cuozzo, John W.,Lavu, Siva,Mao, Cheney,Vlasuk, George P.,Perni, Robert B.
, p. 3666 - 3679 (2013/06/27)
The sirtuins SIRT1, SIRT2, and SIRT3 are NAD+ dependent deacetylases that are considered potential targets for metabolic, inflammatory, oncologic, and neurodegenerative disorders. Encoded library technology (ELT) was used to affinity screen a 1
