1431465-63-2

Upstream product

• 457628-49-8 2-bromo-4-fluoro-1-(prop-2-yn-1-yloxy)benzene 
• 13329-40-3 4-Iodoacetophenone 

Downstream Products

• 1431465-50-7 (E)-1-(4-((4-fluoro-3-methylphenyl)(5-fluorobenzofuran3(3H)-ylidene)methyl)phenyl)ethanone 
• 1431465-35-8 (E)-methyl 4-((4-acetylphenyl)(5-fluorobenzofuran-3(3H)-ylidene)methyl)benzoate 
• 1431465-36-9 (Z)-1-(4-((5-fluorobenzofuran-3(2H)-ylidene)(phenyl)methyl)phenyl)ethanone 

Relevant academic research and scientific papers

Palladium-catalyzed cascade reactions of 1-(3-arylprop-2-ynyloxy)-2-bromo benzene derivatives with organoboron compounds

Applications of the cascade cyclocarbopalladation reaction followed by Suzuki-Miyaura coupling reactions of the readily available aryl-substituted propargylic aryl ethers with arylboronic acid and potassium trans-β- styryltrifluoroborate accomplish a new versatile entry in the synthesis of benzofuran derivatives. Notably, a new approach to the challenging synthesis of C3 functionalized 2-unsubstituted benzofurans has been developed by a cyclocarbopalladation/cross-coupling/aromatization process.