1431853-30-3Relevant articles and documents
Total synthesis of (+)-hyacinthacine A6 and (+)-hyacinthacine A7
Smith, Julien,Kamath, Anushree,Greene, Andrew E.,Delair, Philippe
, p. 209 - 212 (2014/02/14)
(+)-Hyacinthacines A6 and A7 have been synthesized from a common, late-stage intermediate, prepared in high yield through stereoselective [2+2] cycloaddition of dichloroketene to a chiral enol ether. The flexibility of aminonitrile chemistry is central to the approach. Georg Thieme Verlag Stuttgart New York.
Asymmetric approach to hyacinthacines B1 and B2
Reddy, Paidi Venkatram,Smith, Julien,Kamath, Anushree,Jamet, Hélène,Veyron, Ama?l,Koos, Peter,Philouze, Christian,Greene, Andrew E.,Delair, Philippe
, p. 4840 - 4849 (2013/07/05)
Naturally occurring hyacinthacines B1 and B2 have been prepared from a common, easily available, advanced intermediate. The approach features several highly stereoselective transformations: inter alia, a dichloroketene-enol ether [2 + 2] cycloaddition, a Bruylants alkylation, and an amino-nitrile alkylation-reduction.
