1432044-29-5

Basic information

• Product Name: 1,1'-{2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1':3',1''-terphenyl]-4,4''-diyl}bis(ethan-1-one)
• Synonyms: 1,1'-{2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1':3',1''-terphenyl]-4,4''-diyl}bis(ethan-1-one)
• CAS NO: 1432044-29-5
• Molecular Weight: 472.546
• Mol File: 1432044-29-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,1'-{2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1':3',1''-terphenyl]-4,4''-diyl}bis(ethan-1-one)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-{2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1':3',1''-terphenyl]-4,4''-diyl}bis(ethan-1-one)(1432044-29-5)
• EPA Substance Registry System: 1,1'-{2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1':3',1''-terphenyl]-4,4''-diyl}bis(ethan-1-one)(1432044-29-5)

Safety Data

• Hazardous Substances Data: 1432044-29-5(Hazardous Substances Data)

Upstream product

• 28386-90-5 5-benzyl-1-phenyl-1H-tetrazole 
• 99-90-1 para-bromoacetophenone 

Relevant articles and documents

Single-Component Phosphinous Acid Ruthenium(II) Catalysts for Versatile C-H Activation by Metal-Ligand Cooperation

Well-defined ruthenium(II) phosphinous acid (PA) complexes enabled chemo-, site-, and diastereoselective C-H functionalization of arenes and alkenes with ample scope. The outstanding catalytic activity was reflected by catalyst loadings as low as 0.75 mol %, and the most step-economical access reported to date to angiotensin II receptor antagonist blockbuster drugs. Mechanistic studies indicated a kinetically relevant C-X cleavage by a single-electron transfer (SET)-type elementary process, and provided evidence for a PA-assisted C-H ruthenation step. A blockbuster catalyst: Well-defined ruthenium(II) phosphinous acid (PA) complexes were identified as powerful catalysts for highly selective C-H arylations with ample scope, which enabled low catalyst loadings and gave step-economical access to blockbuster drugs. Mechanistic studies were supportive of a PA-assisted C-H activation.