18880-05-2

Basic information

• Product Name: 3-Methoxybenzyltriphenylphosphonium chloride
• Synonyms: 3-METHOXYBENZYLTRIPHENYLPHOSPHONIUM CHLORIDE;[(3-Methoxyphenyl)methyl]triphenylphosphonium chloride;3-Methoxybenzyltriphenylphosphonium chloride, 98 %;[(3-Methoxyphenyl)Methyl]triphenylphosphaniuM chloride
• CAS NO: 18880-05-2
• Molecular Formula: C₂₆H₂₄OP*Cl
• Molecular Weight: 418.89
• Mol File: 18880-05-2.mol
• Article Data: 16

Chemical Properties

• Melting Point: 271-272 °C
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 3-Methoxybenzyltriphenylphosphonium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methoxybenzyltriphenylphosphonium chloride(18880-05-2)
• EPA Substance Registry System: 3-Methoxybenzyltriphenylphosphonium chloride(18880-05-2)

Safety Data

• Hazardous Substances Data: 18880-05-2(Hazardous Substances Data)

Usage

Uses

(3-Methoxybenzyl)(triphenyl)phosphonium Chloride is an intermediate used in the synthesis of 2-Hydroxychrysene (H905340), which is a hydroxylated metabolite of Chrysene (C428000). Binding activity of 2-Hydroxychrysene to estrogenic receptor induces toxicity.

InChI:InChI=1/C26H24OP.ClH/c1-27-23-13-11-12-22(20-23)21-28(24-14-5-2-6-15-24,25-16-7-3-8-17-25)26-18-9-4-10-19-26;/h2-20H,21H2,1H3;1H/q+1;/p-1

Upstream product

• 603-35-0 triphenylphosphine 
• 824-98-6 m-methoxybenzyl chloride 
• 591-31-1 3-methoxy-benzaldehyde 
• 6971-51-3 3-methoxybenzyl alcohol 

Downstream Products

• 168700-28-5 (E/Z)-4-Fluoro-3'-methoxystilbene 
• 485805-43-4 3-(3-methoxystyryl)-2,4,4-trimethyl-1-cyclohexene 
• 626-20-0 3-methoxystyrene 
• 485805-44-5 3-(3-methoxyphenethyl)-2,4,4-trimethyl-1-cyclohexene 
• 168700-26-3 erythro/threo-1,2-Diazido-1-(4-fluorophenyl)-2-(3-methoxyphenyl)ethane 
• 1012321-27-5 1-[(E/Z)-2-(3-methoxy)phenylvinyl]-2-nitrobenzene 
• 1421638-89-2 methyl (1S,3S)-3-[(Z)-2-(3-methoxyphenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-88-1 methyl (1S,3S)-3-[(E)-2-(3-methoxyphenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 14064-41-6 (E)-3-methoxystilbene 
• 39032-14-9 1-[(E)-2-(4-methoxyphenyl)ethenyl]-3-methoxybenzene 
• 20657-34-5 1-methoxy-3-[(Z)-2-(3-methoxyphenyl)vinyl]benzene 
• 6325-63-9 (E)-3,3'-dimethoxystilbene 
• 36707-27-4 1,2-bis(3-methoxyphenyl)ethane 

Relevant articles and documents

In vitro study and structure-activity relationship analysis of stilbenoid derivatives as powerful vasorelaxants: Discovery of new lead compound

The development of vasorelaxant as the antihypertensive drug is important as it produces a rapid and direct relaxation effect on the blood vessel muscles. Resveratrol (RV), as the most widely studied stilbenoid and the lead compound, inducing the excellent vasorelaxation effect through the multiple signalling pathways. In this study, the in vitro vascular response of the synthesized trans-stilbenoid derivatives, SB 1-8e were primarily evaluated by employing the phenylephrine (PE)-precontracted endothelium-intact isolated aortic rings. Herein we report trans-3,4,4′-trihydroxystilbene (SB 8b) exhibited surprisingly more than 2-fold improvement to the maximal relaxation (Rmax) of RV. This article also highlights the characterization of the aromatic protons in terms of their unique splitting patterns in 1H NMR.

Well-defined cyclopropenone-masked dibenzocyclooctyne functionalized polymers from atom transfer radical polymerization

Two functional atom transfer radical polymerization (ATRP) initiators (I-2 and I-3) were developed bearing a cyclopropenone-masked dibenzocyclooctyne group. ATRP was then explored on three main kinds of monomers for radical polymerization including acryla

SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity

Starting from the previously developed P-gp ligands 1a and 1b (EC 50 = 0.25 μM and 0.65 μM, respectively), new arylmethyloxyphenyl derivatives have been synthesized as P-gp modulators in order to investigate: (i) the effect of small electron-do