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143224-64-0

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143224-64-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 143224-64-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,2,2 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 143224-64:
(8*1)+(7*4)+(6*3)+(5*2)+(4*2)+(3*4)+(2*6)+(1*4)=100
100 % 10 = 0
So 143224-64-0 is a valid CAS Registry Number.

143224-64-0Relevant articles and documents

Self-emulsifying drug delivery system

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Page 8, (2010/02/05)

Oral pharmaceutical formulation which improves the bioavailability of pharmaceuticals which are substantially water and oil insoluble is disclosed. In addition to the pharmaceutical, the formulation includes an emulsifier, an oil and an solubilizer. Alter

Epoxide formation by continuous in-situ synthesis process

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, (2008/06/13)

In a method of preparing an aminoepoxide wherein a protected aminoaldehyde is reacted with a halomethyl organometallic reagent in an appropriate solvent at a temperature above -80 DEG C., wherein said halomethyl organometallic reagent is formed by reaction between an organometallic reagent and a dihalomethane, the improvement comprising flowing said protected aminoaldehyde into a mixing zone maintained at a temperature below 0 DEG C., also flowing said halomethyl organometallic reagent in said mixing zone for contacting in said mixing zone with said protected aminoaldehyde and also withdrawing from said mixing zone reaction products of said protected aminoaldehyde and said halomethyl organometallic reagent.

A Practical Synthesis of an HIV Protease Inhibitor Intermediate - Diastreoselective Epoxide Formation from Chiral α-Aminoaldehydes

Ng, John S.,Przybyla, Claire A.,Liu, Chin,Yen, Joe C.,Muellner, Frank W.,Weyker, Cara L.

, p. 6397 - 6410 (2007/10/02)

A practical and efficient synthesis of an HIV protease inhibitor intermediate has been developed based on the diastereoselective epoxide formation from a chiral α-aminoaldehyde and an in situ generated halomethyllithium reagent.

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