143236-60-6

Upstream product

• 136320-64-4 (2R)-3-[(4-methoxybenzyl)oxy]-2-methylpropanol 
• 143236-59-3 2-[(S)-3-(4-Methoxy-benzyloxy)-2-methyl-propoxy]-tetrahydro-pyran 

Downstream Products

• 1266178-48-6 C₄₅H₆₉BrO₆Si₂ 
• 1266178-49-7 C₄₅H₆₉BrO₆Si₂ 
• 863663-18-7 (2R,4R)-2-[(4S,5R)-3-((1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-methylethyl)-4-methyl-4,5-dihydroisoxazol-5-yl]-5-[(4-methoxybenzyl)oxy]-4-methylpentan-2-ol 
• 143236-65-1 (E)-(6S,9R)-1-(tert-Butyl-dimethyl-silanyloxy)-6-hydroxy-10-(4-methoxy-benzyloxy)-3,9-dimethyl-dec-2-en-4-one 
• 143236-63-9 (3S,6R)-3-Hydroxy-7-(4-methoxy-benzyloxy)-6-methyl-heptanoic acid methoxy-methyl-amide 
• 143236-62-8 (3S,6R)-3-Hydroxy-7-(4-methoxy-benzyloxy)-6-methyl-heptanoic acid methyl ester 
• 143236-61-7 (R)-7-(4-Methoxy-benzyloxy)-6-methyl-3-oxo-heptanoic acid methyl ester 

Relevant academic research and scientific papers

Stereoselective synthesis of erythronolide A via nitrile oxide cycloadditions and related studies

(Chemical Equation Presented) An expeditious synthesis of erythronolide A is documented. Key steps of the approach include two magnesium-mediated nitrile oxide cycloadditions, a chelation-controlled Grignard reaction, and a Sharpless asymmetric dihydroxylation. 2009 American Chemical Society.

Synthetic Investigations of Rapamycin. 1. Synthesis of a C10-C21 Fragment

Phosphine oxide 2, representing the C10-C21 portion of rapamycin, was stereoselectively synthesized and was demonstrated to undergo a Horner-Wittig reaction to form triene 25 as an 8:1 mixture of trans-cis isomers.