143236-65-1Relevant academic research and scientific papers
Synthetic Investigations of Rapamycin. 1. Synthesis of a C10-C21 Fragment
Meyer, Stephanie D.,Miwa, Tetsuo,Nakatsuka, Masashi,Schreiber, Stuart L.
, p. 5058 - 5060 (1992)
Phosphine oxide 2, representing the C10-C21 portion of rapamycin, was stereoselectively synthesized and was demonstrated to undergo a Horner-Wittig reaction to form triene 25 as an 8:1 mixture of trans-cis isomers.
