143239-02-5

Basic information

• Product Name: (2S)-3-[3-(benzyloxy)phenyl]-2-methylpropyl acetate
• CAS NO: 143239-02-5
• Molecular Formula: C₁₉H₂₂O₃
• Molecular Weight: 298.3762
• Mol File: 143239-02-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 425.4°C at 760 mmHg
• Flash Point: 181.2°C
• Density: 1.077g/cm³
• Vapor Pressure: 1.91E-07mmHg at 25°C
• Refractive Index: 1.542
• CAS DataBase Reference: (2S)-3-[3-(benzyloxy)phenyl]-2-methylpropyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-3-[3-(benzyloxy)phenyl]-2-methylpropyl acetate(143239-02-5)
• EPA Substance Registry System: (2S)-3-[3-(benzyloxy)phenyl]-2-methylpropyl acetate(143239-02-5)

Safety Data

• Hazardous Substances Data: 143239-02-5(Hazardous Substances Data)

Upstream product

• 108-05-4 vinyl acetate 
• 141-78-6 ethyl acetate 
• 143291-83-2 3-(3-Benzyloxy-phenyl)-2-methyl-propan-1-ol 

Downstream Products

• 146628-93-5 Acetic acid (S)-3-(3-methanesulfonyloxy-phenyl)-2-methyl-propyl ester 
• 79211-56-6 (2S)-2-methyl-3-phenylpropyl acetate 
• 7384-80-7 (S)-2-methyl-3-phenylpropan-1-ol 
• 143239-00-3 (S)-3-(3-Benzyloxy-phenyl)-2-methyl-propan-1-ol 

Relevant articles and documents

Kinetic resolution of primary 2-methyl-substituted alcohols via Pseudomonas cepacia lipase-catalysed enantioselective acylation

The enantioselectivities of lipases from Pseudomonas cepacia (PFL, Amano PS, etc.) towards a series of primary 2-methyl-substituted alcohols using vinyl acetate as the acyl donor in transesterifications in organic solvents were studied. In terms of enantioselectivity, the best results were found for 3-aryl-2-methylpropan-1-ols with enantiomeric ratios (E-values) over 100 in most cases, whereas other 3-substituted primary 2-methylpropan-1-ols generally displayed lower enantioselectivities: 3-cycloalkyl-2-methylpropan-1-ols (E ≈ 20) and 2-methylalkan-1-ols (E ≈ 10). Moving the aryl group closer or further away from the chiral centre resulted in low enantioselectivities: 2-arylpropan-1-ols (E 10), 2-methyl-4-(2-thienyl)butan-1-ol (E = 12), 2-methyl-5-(2-thienyl)pentan-1-ol (E = 3.2) and 2-methyl-6-(2-thienyl)hexan-1-ol (E = 3.8).