143264-74-8

Upstream product

• 143264-72-6 N-p-toluenesulphonyl(5-diphenyl-tert-butylsilyloxymethyl)-2-hydroxypyrrolidine 
• 132974-84-6 (-)-(5S)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}-1-tosylpyrrolidin-2-one 
• 143264-73-7 N-p-toluenesulphonyl(5-diphenyl-tert-butylsilyloxymethyl)-2-methoxypyrrolidine 

Downstream Products

• 143264-79-3 (2R,5R)-2-Methoxy-1-(toluene-4-sulfonyl)-5-((E)-5-trimethylsilanyl-pent-4-enyl)-pyrrolidine 
• 143264-76-0 (E)-6-[(2R,5R)-5-Methoxy-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-hex-3-en-2-one 
• 143264-78-2 4-[(2R,5R)-5-Methoxy-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-butan-1-ol 
• 143264-80-6 (1R,6R)-9-(Toluene-4-sulfonyl)-2-vinyl-9-aza-bicyclo[4.2.1]nonane 
• 143264-75-9 (2R,5R)-2-But-3-enyl-5-methoxy-1-(toluene-4-sulfonyl)-pyrrolidine 
• 64285-06-9 anatoxin-a 

Relevant academic research and scientific papers

A short and enantioselective synthesis of (+)-Anatoxin-a

A short and enantioselective total synthesis of the neurotoxic alkaloid (+)-Anatoxin-a (1) from the L-pyroglutamic acid derivative 2 is described. The key step involves an intramolecular cyclisation of an N-tosyl iminium ion derived from the corresponding α-methoxy sulfonamide.