143287-94-9

Basic information

• Product Name: 4-PHENYLCYCLOHEX-1-ENE-1-CARBOXYLIC ACID
• Synonyms: 4-PHENYLCYCLOHEX-1-ENE-1-CARBOXYLIC ACID;4-phenylcyclohex-1-enecarboxylic acid
• CAS NO: 143287-94-9
• Molecular Formula: C₁₃H₁₄O₂
• Molecular Weight: 202.24906
• Mol File: 143287-94-9.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-PHENYLCYCLOHEX-1-ENE-1-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PHENYLCYCLOHEX-1-ENE-1-CARBOXYLIC ACID(143287-94-9)
• EPA Substance Registry System: 4-PHENYLCYCLOHEX-1-ENE-1-CARBOXYLIC ACID(143287-94-9)

Safety Data

• Hazardous Substances Data: 143287-94-9(Hazardous Substances Data)

Usage

General Description

4-Phenylcyclohex-1-ene-1-carboxylic acid, also known as 4-phenylcyclohexene-1-carboxylic acid, is a chemical compound with the molecular formula C13H14O2. It is a carboxylic acid derivative with a phenyl group attached to a cyclohexene ring. 4-PHENYLCYCLOHEX-1-ENE-1-CARBOXYLIC ACID is primarily used in organic synthesis for the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as a building block in the synthesis of various compounds, and its unique structure makes it a valuable tool in drug discovery and development. The compound's properties and functional groups make it an important starting material for the synthesis of various complex organic compounds.

Upstream product

• 1248776-24-0 1-hydroxy-4-phenyl-cyclohexanecarboxylic acid 
• 7732-18-5 water 
• 75-25-2 Bromoform 
• 4894-75-1 1-phenyl-4-cyclohexanone 
• 124-38-9 carbon dioxide 
• 287944-05-2 4,4,5,5-tetramethyl-2-(1,2,3,6-tetrahydro-[1,1'-biphenyl]-4-yl)-1,3,2-dioxaborolane 
• 63113-14-4 4-phenyl-1-chlorocyclohexene 
• 92-92-2 biphenyl-4-carboxylic acid 
• 7494-76-0 trans-4-phenylcyclohexane carboxylic acid 
• 2920-38-9 4-cyano-1,1'-biphenyl 
• 22748-63-6 1,2,3,6-tetrahydro-[1,1′-biphenyl]-4-carbonitrile 
• 122948-47-4 4-phenylcyclohex-1-enyl trifluoromethanesulfonate 
• 201230-82-2 carbon monoxide 

Downstream Products

• 873949-18-9 ethyl 4-phenyl-1-cyclohexenecarboxylate 
• 1466-73-5 trans-4-phenylcyclohexanecarboxylic acid 
• 56288-51-8 (1s,4s)-4-phenylcyclohexane-1-carboxylic acid 
• 83811-73-8 trans-4-phenylcyclohexylmethanol 
• 22787-67-3 4-Phenyl-cyclohex-1-enecarboxylic acid methyl ester 

Relevant articles and documents

Palladium-Catalyzed Carboxylation of Vinyl Triflates. Electrosynthesis of α, β-Unsaturated Carboxylic Acids

The electrocarboxylation of vinyl triflates performed with carbon dioxide and a catalytic amount of PdCl2(PPh3)2 affords α,β-unsaiurated carboxylic acids. The reactivity of vinyl triflates has been reversed in the presence of an electron source, since they now react with electrophiles. The reaction proceeds by an activation of the C-O bond of the vinyl triflate by a palladium(O) complex followed by an activation by electron transfer, of the vinylpalladium(II) complex formed in the oxidative addition.

Method for preparing alpha, beta-unsaturated carboxylic acid by reacting alkenyl boron compound with carbon dioxide under catalysis of cuprous halide

The invention discloses a method for preparing alpha, beta-unsaturated carboxylic acid through a carboxylation reaction of an alkenyl boron compound and carbon dioxide under the catalysis of cuprous halide. According to the method, carbon dioxide is used as a C1 source, the cuprous halide is adopted for catalysis, and alkoxide serves as alkali to react in an organic solvent, so the method is simple and easy to implement, has a wide substrate application range, converts various alkenyl boron compounds such as alkenyl boric acid, alkenyl borate and borate into corresponding alpha, beta-unsaturated carboxylic acid under mild conditions, and has a very high yield. The obtained product alpha, beta-unsaturated carboxylic acid is an important intermediate for preparing fine chemical products suchas perfumes, insecticides and the like.

Palladium-Catalyzed Visible-Light-Driven Carboxylation of Aryl and Alkenyl Triflates by Using Photoredox Catalysts

A visible-light-driven carboxylation of aryl and alkenyl triflates with CO2 is developed by using a combination of Pd and photoredox catalysts. This reaction proceeds under mild conditions and can be applied to a wide range of substrates including acyclic alkenyl triflates.