143317-74-2

Usage

Uses

Used in Pharmaceutical Industry:
Erucylphosphocholine is used as an anticancer agent for its ability to induce apoptosis in cancer cells. It is particularly effective against solid malignancies such as pancreatic and colorectal cancers, disrupting the cell membrane and altering lipid metabolism to cause cancer cell death.
Used in Anti-inflammatory Applications:
Erucylphosphocholine is used as an anti-inflammatory agent for its potential role in reducing inflammation in conditions such as arthritis. Further research is needed to fully understand its mechanisms of action and therapeutic uses in this area.

InChI:InChI=1/C27H56NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-26-31-33(29,30)32-27-25-28(2,3)4/h12-13H,5-11,14-27H2,1-4H3/b13-12-

Upstream product

• 629-98-1 erucyl alcohol 
• 75-50-3 trimethylamine 

Relevant academic research and scientific papers

Antitumor phospholipids: A one-pot introduction of a phosphocholine moiety into lipid hydroxy acceptors

A high-yielding, 3-step, one-pot conversion of lipid hydroxy acceptors 2 into clinically useful alkylphosphocholines 1 is reported. Reaction of 2 with ethylene chlorophosphite gave phosphite 3, which underwent oxidation and ring opening with bromine in CH2Cl2 to give (2-bromoethyl)phosphate ester 4; hydrolysis of the P-Br bond and quaternization of 4 with aqueous trimethylamine generated 1.

Novel alkyl phospholipid derivatives and uses thereof

The present invention provides novel alkyl phospholipid derivatives that are useful for treating various diseases including tumors and/or pathophysiological conditions in mammals, preferably humans, that are caused by microorganisms, in particular fungi, protozoa, bacteria and/or viruses. Such alkyl phospholipids can be employed as single drugs or in the course of combination therapies, in particular for the treatment of leishmaniasis, trypanosomiasis and/or malaria.