14334-36-2

Usage

Molecular Weight

196.25 g/mol

Appearance

White solid

Melting Point

146-148°C

Solubility

Soluble in organic solvents such as acetone, methanol, and ethyl acetate

Uses

a. Curing agent for epoxy resins
b. Stabilizer for plastics and rubbers
c. Component in hair dyes and color products
d. Antioxidant in the production of adhesives, sealants, and coatings

Safety Precautions

a. May cause skin and eye irritation
b. Harmful if inhaled or ingested
c. Handle with care and follow safety instructions

Upstream product

• 127-19-5 N,N-dimethyl acetamide 
• 16766-92-0 1,3-Bis-tribrommethyl-benzol 
• 121-91-5 isophthalic acid 
• 68-12-2 N,N-dimethyl-formamide 
• 124-40-3 dimethyl amine 
• 99-63-8 benzene-1,3-dicarbonyl dichloride 

Downstream Products

• 171562-86-0 (CO)5Cr((C(N(CH₃)2))2C₆H₄)Fe(CO)4 
• 171562-75-7 [(CO)4Fe]2((C(N(CH₃)2))2C₆H₄) 
• 171562-74-6 [(CO)5Cr]2((C(N(CH₃)2))2C₆H₄) 
• 171562-80-4 (CO)5Cr(C(N(CH₃)2)C₆H₄OCN(CH₃)2) 

Relevant academic research and scientific papers

Acid-induced conformational alteration of cis-preferential aromatic amides bearing N-methyl-N-(2-pyridyl) moiety

A series of cis-preferential aromatic N-methyl amides was designed and synthesized, and acid-induced conformational alteration of these compounds was investigated by means of NMR measurements in solution and X-ray crystal structure analysis. Compounds with a terminal N-methyl-N-(2-pyridyl) amide unit showed acid-induced conformational change from cis to trans, while those with a terminal N-methyl-2-pyridinecarboxamide unit showed a change of the carbonyl orientation from anti to syn with retention of cis conformation.

An effective synthesis of N,N-dimethylamides from carboxylic acids and a new route from N,N-dimethylamides to 1,2-diaryl-1,2-diketones

Carboxylic acids were heated at 150 °C in DMF in the presence of 1.25 equiv of thionyl chloride to give corresponding N,N-dimethylamides in good yields. Tandem chlorination and amidation reactions occurred in the one-pot procedure. Dicarboxylic acids needed prolonged reaction time to produce bisamides in good yields. Some benzamides were efficiently converted into corresponding 1,2-diaryl-1,2-diketones (benzils) under acyloin condensation conditions in the presence of 4,4′-di-tert-butylbiphenyl (DBB) in THF. Ultrasonic irradiation effectively accelerates the reaction, but it is not critical. However, the presence of DBB is fatal to the reaction. Although a few synthetic methods for benzils from benzoic acids have been reported so far, this method is one of the most convenient and highly reproducible procedures.

Palladium(0) complex-catalyzed debrominative coupling of (tribromomethyl)- and (dibromomethyl)benzenes to diarylacetylenes and 1,2-diarylethenes

Palladium(0)-triphenylphosphine complex-catalyzed debrominative coupling reaction of (tribromomethyl)benzenes gave diarylacetylenes or a mixture of (E)- and (Z)-α,β-dibromostilbenes depending upon the substrate and the solvent being used. On the other hand, (dibromomethyl)benzenes afforded (E)-stilbenes selectively under the same reaction conditions.