1433716-62-1

Basic information

• Product Name: N-(3-{4-[(cyclopropylaminocarbonyl)amino]phenyl}-1H-5-pyrazolyl)-4-(4-methylpiperazino)benzamide
• Synonyms: N-(3-{4-[(cyclopropylaminocarbonyl)amino]phenyl}-1H-5-pyrazolyl)-4-(4-methylpiperazino)benzamide
• CAS NO: 1433716-62-1
• Molecular Weight: 459.551
• Mol File: 1433716-62-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-{4-[(cyclopropylaminocarbonyl)amino]phenyl}-1H-5-pyrazolyl)-4-(4-methylpiperazino)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-{4-[(cyclopropylaminocarbonyl)amino]phenyl}-1H-5-pyrazolyl)-4-(4-methylpiperazino)benzamide(1433716-62-1)
• EPA Substance Registry System: N-(3-{4-[(cyclopropylaminocarbonyl)amino]phenyl}-1H-5-pyrazolyl)-4-(4-methylpiperazino)benzamide(1433716-62-1)

Safety Data

• Hazardous Substances Data: 1433716-62-1(Hazardous Substances Data)

Upstream product

• 401495-67-8 4-(4-methylpiperazin-4-ium-1-yl)benzoyl chloride 
• 78583-83-2 5-amino-3-(4-nitrophenyl)-1H-pyrazole 
• 1327167-35-0 N-[3-(4-aminophenyl)-1H-5-pyrazolyl]-4-(4-methylpiperazino)benzamide 
• 4747-72-2 isocyanatocyclopropane 

Relevant articles and documents

Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)

Preclinical investigations and early clinical trials suggest that FLT3 inhibitors are a viable therapy for acute myeloid leukemia. However, early clinical data have been underwhelming due to incomplete inhibition of FLT3. We have developed 3-phenyl-1H-5-p