1433902-86-3

Upstream product

• 719-59-5 5-chloro-2-aminobenzophenone 
• 93654-27-4 6-chloro-2-oxo-4-phenyl-1,2-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 105-53-3 diethyl malonate 
• 110-91-8 morpholine 
• 307329-52-8 2,6-dichloro-4-phenyl-quinoline-3-carboxylic acid ethyl ester 

Downstream Products

• 1433901-59-7 6-chloro-2-morpholin-4-yl-4-phenyl-quinoline-3-carboxylic acid 

Relevant academic research and scientific papers

NEW ARYL-QUINOLINE DERIVATIVES

The invention provides novel compounds having the general formula (I), wherein R1, R2, R3, R4 R5, R6 and n are as described herein, compositions including the compounds and methods of using the compounds.

ARYL-QUINOLINE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6 and n are as described herein, compositions including the compounds and methods of using the compounds. The present compounds are useful as fatty-acid binding protein (FABP) 4 and/or 5 inhibitors and may be used for the treatment or prophylaxis of lipodystrophy, type 2 diabetes, dyslipidemia, atherosclerosis, liver diseases involving inflammation, steatosis and/or fibrosis, such as non-alcoholic fatty liver disease, in particular non-alcoholic steatohepatitis, metabolic syndrome, obesity, chronic inflammatory and autoimmune inflammatory diseases.