1434141-90-8 Usage
Description
Tert-butyl (2,2-dimethyl-3-oxocyclobutyl)carbamate, also known as Boc-3-oxocyclobutylamine, is a chemical compound that serves as a protecting group for amines in organic synthesis. It is a derivative of the Boc (tert-butyloxycarbonyl) group, which is extensively utilized in peptide synthesis and other organic reactions to shield the amine functionality. tert-butyl (2,2-dimethyl-3-oxocyclobutyl)carbamate is distinguished by its cyclobutane ring with a carbamate group, a tert-butyl group, and two methyl groups attached to one of the carbon atoms. It is favored for selectively protecting amine groups in the presence of other functional groups and can be deprotected under mild conditions to yield the free amine.
Uses
Used in Organic Synthesis:
Tert-butyl (2,2-dimethyl-3-oxocyclobutyl)carbamate is used as a protecting group for amines during organic synthesis for the reason that it allows selective protection of amine groups in the presence of other functional groups, facilitating complex organic reactions without unwanted side reactions.
Used in Peptide Synthesis:
In the pharmaceutical and biotechnology industries, tert-butyl (2,2-dimethyl-3-oxocyclobutyl)carbamate is used as a protecting agent for amines in peptide synthesis to prevent unwanted side reactions during the formation of peptide bonds, ensuring the correct sequence and structure of the peptide.
Used in Chemical Research:
Tert-butyl (2,2-dimethyl-3-oxocyclobutyl)carbamate is utilized as a reagent in chemical research for the study of amine protection and deprotection strategies, contributing to the development of new synthetic routes and methodologies in organic chemistry.
Used in Drug Development:
In the development of new pharmaceuticals, tert-butyl (2,2-dimethyl-3-oxocyclobutyl)carbamate is employed as a protecting group to facilitate the synthesis of complex drug molecules containing amine groups, enhancing the efficiency and selectivity of the synthesis process.
Check Digit Verification of cas no
The CAS Registry Mumber 1434141-90-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,4,1,4 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1434141-90:
(9*1)+(8*4)+(7*3)+(6*4)+(5*1)+(4*4)+(3*1)+(2*9)+(1*0)=128
128 % 10 = 8
So 1434141-90-8 is a valid CAS Registry Number.
1434141-90-8Relevant articles and documents
SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
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Paragraph 0208, (2015/07/02)
Provided herein are diaminopyrimidyl Compounds having the following structures: wherein X, L, R1, and R2 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidyl Compound, and methods for treating or preventing PKC-theta-mediated disorders, or a condition treatable or preventable by inhibition of a kinase, for example, PKC-theta.
