143416-42-6Relevant articles and documents
Characterization of the LM5 pectic galactan epitope with synthetic analogues of β-1,4-D-galactotetraose
Andersen, Mathias C.F.,Boos, Irene,Marcus, Susan E.,Kra?un, Stjepan K.,Rydahl, Maja Gro,Willats, William G.T.,Knox, J. Paul,Clausen, Mads H.
supporting information, p. 36 - 40 (2016/11/23)
Plant cell wall glycans are important polymers that are crucial to plant development and serve as an important source of sustainable biomass. The study of polysaccharides in the plant cell wall relies heavily on monoclonal antibodies (mAbs) for localizati
A strategy for chemical synthesis of selectively methyl-esterified oligomers of galacturonic acid
Clausen, Mads H.,Jorgensen, Malene R.,Thorsen, Jesper,Madsen, Robert
, p. 543 - 551 (2007/10/03)
The synthesis of monomethyl-esterified trigalacturonans 1-3 is described as part of a general strategy towards pectic oligosaccharides. The necessary monomeric building blocks were all prepared on a large scale from galactose pentaacetate. The glycosylations were carried out between galactose glycosyl donors and acceptors using the n-pentenyl glycosylation technique. Yields of the desired α-anomers were in the 50 to 74% range. The trigalactans thus obtained were then subjected to oxidation at C-6. Depending on the protecting group at this position the oxidation either produced the carboxylic acid or the corresponding methyl ester. Hereby, oligomers of galacturonic acid can be prepared with methyl esters introduced in a regiocontrolled fashion.