143466-47-1

Basic information

• Product Name: (+/-)-N-Benzyl aspidospermidine
• Synonyms: (+/-)-N-Benzyl aspidospermidine
• CAS NO: 143466-47-1
• Molecular Weight: 372.553
• Mol File: 143466-47-1.mol

Chemical Properties

• CAS DataBase Reference: (+/-)-N-Benzyl aspidospermidine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-N-Benzyl aspidospermidine(143466-47-1)
• EPA Substance Registry System: (+/-)-N-Benzyl aspidospermidine(143466-47-1)

Safety Data

• Hazardous Substances Data: 143466-47-1(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 7689-02-3 aspidospermidine 
• 1448446-88-5 C₂₆H₂₈N₂O₂ 
• 1448446-92-1 C₂₈H₃₂N₂O₃ 
• 1448446-91-0 C₂₁H₂₆N₂O₃ 
• 1448446-87-4 C₁₁H₁₉NO₂ 
• 1448446-90-9 C₁₉H₂₅NO₄ 
• 1448446-86-3 2-aza-2-benzyloxycarbonyl-6-ethylbicyclo[4.2.0]octan-7-one 
• 87-51-4 indole-3-acetic acid 
• 1448447-16-2 C₁₇H₁₉Cl₂NO₃ 
• 1246190-33-9 3,4-dihydro-2H-5-ethylpyridine-1-carboxylic acid benzyl ester 
• 19716-82-6 1-(phenylmethyl)-3-ethyl-1,4,5,6-tetrahydropyridine 
• 143504-56-7 (3aR,5aR,10bR)-6-Benzyl-3a-ethyl-1,2,3,3a,4,5,5a,6,11,12-decahydro-6-aza-12a-azonia-indeno[7,1-cd]fluorene; chloride 

Relevant articles and documents

Regioselective inter- and intramolecular formal [4+2] cycloaddition of cyclobutanones with indoles and total synthesis of (±)-aspidospermidine

This way and that way: A formal [4+2] cycloaddition between various cyclobutanones and indoles proceeded efficiently under Lewis acid catalysis (see scheme; PG = protecting group). The regioselectivity of the reaction could be controlled in such a way that each of the two possible regioisomers of a cycloaddition product could be synthesized selectively. The usefulness of this reaction for the total synthesis of hydrocarbazole natural products was demonstrated. Copyright

A Short Synthesis of (+/-) N-Benzyl Aspidospermidine

(+/-) N-Benzyl aspidospermidine is synthesized in seven steps via the trisubstituted hexahydrocarbazolone 4; reductive cyclization of this intermediate which is obtained by photocyclization and Michael reaction with nitroethylene, creates simulteanously b