143543-74-2

Basic information

• Product Name: 2-Thiazolamine, N-[(2,4-dichlorophenyl)methyl]-4,5-dihydro-
• CAS NO: 143543-74-2
• Molecular Formula: C10H10Cl2N2S
• Molecular Weight: 261.175
• Mol File: 143543-74-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Thiazolamine, N-[(2,4-dichlorophenyl)methyl]-4,5-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiazolamine, N-[(2,4-dichlorophenyl)methyl]-4,5-dihydro-(143543-74-2)
• EPA Substance Registry System: 2-Thiazolamine, N-[(2,4-dichlorophenyl)methyl]-4,5-dihydro-(143543-74-2)

Safety Data

• Hazardous Substances Data: 143543-74-2(Hazardous Substances Data)

Upstream product

• 95-00-1 2,4-dichloro-benzenemethanamine 
• 52626-40-1 (2,4-dichloro-benzyl)-dithiocarbamic acid; triethylamine salt 
• 18967-41-4 2,4-dichloro-1-(isothiocyanatomethyl)benzene 
• 141-43-5 ethanolamine 

Relevant articles and documents

Synthesis and Octopaminergic Agonist Activity of 2-(Substituted benzylamino)-2-thiazolines

2-(Substituted benzylamino)-2-thiazolines (SBAT) were synthesized by a hydrochloric acid-catalyzed cyclization of the corresponding thioureas, using a reaction of 2-methylthio-2-thiazoline with substituted benzylamines or by alkylating 2-amino-2-thiazoline. 2-(Alkylthio)-2-thiazolines were obtained by alkylating 2-mercaptothiazoline.Most of the SBAT compounds activated adenylate cyclase in homogenates of cockroach ventral nerve cords; the effect of introducing substituents at the phenyl of the SBAT compounds on octopaminergic agonist activity was not significant. 2--2-thiazolines and 2-(alkylthio)-2-thiazolines were not significant octopaminergic agonists.Washing removed nearly all of the activity of one of the SBAT compounds, suggesting that the SBAT compounds bound reversibly to the octopaminergic receptor.