14356-92-4Relevant academic research and scientific papers
Direct trifluoromethylation of nitriles promoted by tetrabutylammonium bifluoride
Huang, Adrian,Li, Huan-Qiu,Massefski, Walter,Saiah, Eddine
experimental part, p. 2518 - 2520 (2010/01/16)
The direct trifluoromethylation of nitriles using TMSCF3 is reported. This reaction is promoted by TBABF and provides ,-bistrifluoromethylated amines in moderate to good yields. The reaction conditions are mild and tolerate a range of functional groups. T
Generation of doubly trifluoromethylsubstituted carbocations: Synthesis of α,α-Bis(trifluoromethyl)benzylamines
Nesi, Marcella,Brasca, Maria Gabriella,Longo, Antonio,Moretti, Walter,Panzeri, Achille
, p. 4881 - 4884 (2007/10/03)
α,α-Bis(trifluoromethylbenzyl)triflates offer a convenient access to the corresponding amines through S(N)1 type reactions.
