1435901-75-9Relevant academic research and scientific papers
Three-step synthesis of novel 2-aryl-3-benzamidobenzofurans: Regiospecific reactions catalyzed by molybdate sulfuric acid
Hashemi, Fatemeh,Karami, Bahador,Khodabakhshi, Saeed
, p. 322 - 326 (2014/04/17)
A solvent-free and synthetic pathway to novel benzofuran derivatives, starting from oxidation of phenyl ketones to arylglyoxals in three steps was developed. The molybdate sulfuric acid catalyzed the reaction of arylglyoxals with benzamide and phenols to afford 2-aryl-3-benzamidobenzofurans in high yield. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR, 1H NMR, and 13C NMR spectral data. The present methodology offers several advantages such as non-hazardous reaction condition, simple operation, and work-up procedure.
One-pot synthesis of benzamidonaphtho[2,1-b]furans and benzamidobenzo[b] furans as novel polycyclic heteroaromatic compounds
Vahabinia, Hamid Reza,Karami, Bahador,Khodabakhshi, Saeed
, p. 1323 - 1327 (2014/04/17)
An operationally simple, green and efficient procedure for one-pot synthesis of novel polycyclic heteroaromatic compounds such as benzamidonaphtho[2,1-b]furans and benzamidobenzo[b]furans has been developed from the reaction of arylglyoxals, benzamide, and phenols. The reactions were mediated with low amounts of yttrium nitrate hexahydrate as a suitable Lewis acid catalyst without using solvent.
Zirconium catalyzed chemoselective synthesis of new amido-substituted benzo[b]furans via a one-pot reaction
Karami, Bahador,Khodabakhshi, Saeed,Vahabinia, Hamid Reza
, p. 399 - 405 (2013/03/28)
A one-pot, three-component reaction of arylglyoxals, benzamide and phenols using catalytic amounts of zirconium oxychloride octahydrate under solvent-free conditions produce new amido-substituted benzo[b]furans. The reactions showed chemoselectivity towards benzofuran instead of oxazols which this claim has been confirmed by nuclear magnetic resonance (NMR) and infrared spectroscopy (IR).
Synthesis of a novel class of benzofurans via a three-component, regiospecific intramolecular heterocylization reaction
Karami, Bahador,Khodabakhshi, Saeed,Hashemi, Fatemeh
supporting information, p. 3583 - 3585 (2013/07/25)
A new, convenient, and environmentally benign three-component synthesis of a novel class of benzofurans is developed by condensing different arylglyoxals, benzamide, and phenolic substrates under solvent-free conditions. These reactions are catalyzed by tungstate sulfuric acid (TSA) as a safe, clean, and recyclable solid acid. The method is operationally simple and provides access to a variety of 2-aryl-3-benzamido benzofurans in good to excellent yields.
