1436413-30-7Relevant articles and documents
Palladium-Based Nanocatalyst for One-Pot Synthesis of Polysubstituted Quinolines
Chen, Benjamin Wei Jie,Chng, Leng Leng,Yang, Jun,Wei, Yifeng,Yang, Jinhua,Ying, Jackie Y.
, p. 277 - 283 (2013)
The synthesis of quinolines has been achieved through a one-pot, two-step tandem reaction catalyzed with Ag-Pd alloy nanoparticles supported on carbon. Ag-Pd alloy nanoparticles catalyzed the coupling of a ketone with a primary alcohol through a hydrogen autotransfer process, which yields α-alkylated ketones under an Ar flow. These are reacted with 2-aminobenzyl alcohols in a modified Friedlaender synthesis to give polysubstituted quinolines in moderate to good yields.