143679-50-9

Upstream product

• 61899-98-7 2,6,6-trimethylcyclohex-2-en-1-ylidene ketene 
• 28102-28-5 (+)-(R)-α-damascone 
• 108-05-4 vinyl acetate 
• 28102-22-9 (6RS,7RS,8SR)-7,8-epoxy-α-dihydroionone 
• 127-41-3 alpha-ionone 
• 143605-74-7 3-Benzyloxy-1-((R)-2,6,6-trimethyl-cyclohex-2-enyl)-butan-1-ol 
• 143605-73-6 3-(benzyloxy)-1-(2,6,6-trimethylcyclohex-2-enyl)butan-2-one 
• 143605-75-8 Acetic acid 3-benzyloxy-1-((R)-2,6,6-trimethyl-cyclohex-2-enyl)-butyl ester 

Downstream Products

• 908297-89-2 (-)-(6S,9S)-7-oxo-α-dihydroionol acetate 
• 116497-11-1 (2E)-1-[(S)-2,6,6-trimethylcyclohex-2-enyl]but-2-en-1-one 

Relevant academic research and scientific papers

Synthesis of the enantiomeric forms of α- and γ-damascone starting from commercial racemic α-ionone

A straightforward synthesis of both enantiomers of α- and γ-damascone is described. The title compounds were prepared by a divergent pathway starting from the enantiomeric forms of (6RS,7SR,9RS)-7-hydroxy-7,8-dihydro-α-ionol and of (6RS,7SR,9RS)-7-hydroxy

Efficient Synthesis of Enantiomerically Pure α-Ionone from (R)- and (S)-α-Damascone

(R)- and (S)-α-ionone ((R)- and (S)-1, resp.) were prepared from (R)- and (S)-α-damascone ((R)- and (S)-3, resp.) without racemization in 48percent yield employing a new enone transposition.The described transposition is complementary to existing methods whose application is often prohibited by the structural requirements of the substrate.The now easily accessible α-ionones of desired absolute configuration are useful as chiral building blocks for terpenoid syntheses.