143745-87-3

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[3-(5-ethyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinyl)propyl]-
• CAS NO: 143745-87-3
• Molecular Formula: C19H20N2O3
• Mol File: 143745-87-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[3-(5-ethyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinyl)propyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[3-(5-ethyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinyl)propyl]-(143745-87-3)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[3-(5-ethyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinyl)propyl]-(143745-87-3)

Safety Data

• Hazardous Substances Data: 143745-87-3(Hazardous Substances Data)

Upstream product

• 143745-99-7 3-hydroxymethylene-2-pentanone sodium salt 
• 143746-01-4 2-methoxy-3-(3-aminopropyl)-5-ethyl-6-methylpyridine 
• 143746-02-5 trans-2-methoxy-3-(2-cyanoethenyl)-5-ethyl-6-methylpyridine 
• 107-87-9 2-Pentanone 
• 139393-90-1 3-cyano-5-ethyl-2-methoxy-6-methylpyridine 
• 139393-89-8 2-chloro-3-cyano-5-ethyl-6-methylpyridine 
• 136562-04-4 3-cyano-5-ethyl-6-methylpyridin-2(1H)-one 
• 136562-05-5 5-ethyl-2-methoxy-6-methylpyridine-3-carboxaldehyde 
• 875283-66-2 2-methoxy-3-(3-phthalimidopropyl)-5-ethyl-6-methylpyridine 

Relevant articles and documents

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1 specific reverse transcriptase inhibitors. 1. Phthalimidoalkyl and -alkylamino analogues

A potent (IC50 = 30 nM), specific nonnucleoside HIV-1 reverse transcriptase (RT) inhibitor 3-[N-(phthalimidomethyl)amino]-5-ethyl-6- methylpyridin-2(1H)-one (1), was discovered through an in vitro screening program. This compound did not inhibi