14375-68-9

Upstream product

• 5042-53-5 1-(phenylsulfanyl)acetone 
• 100-52-7 benzaldehyde 
• 13884-96-3 1-phenylsulfanyl-1-(triphenylphosphoranylidene)-2-propanone 
• 108-98-5 thiophenol 
• 931-59-9 benzenesulfenyl chloride 
• 13307-75-0 (phenylthio)methyllithium 

Downstream Products

• 99789-18-1 r-2-Ethoxy-3,4-dihydro-6-methyl-t-4-phenyl-5-phenylthio-2H-pyran 
• 99789-18-1 r-2-Ethoxy-3,4-dihydro-6-methyl-c-4-phenyl-5-phenylthio-2H-pyran 

Relevant academic research and scientific papers

Diastereoselective synthesis and stereochemistry of (Z)-1-[3-aryl-2- (phenylsulfanyl)-2-oxiranyl]-1-ethanones

Diastereoselective synthesis of a series of (Z)-1-[3-aryl-2- (phenylsulfanyl)-2-oxiranyl]-1-ethanones was effected from the reaction of (Z)-4-aryl-3-(phenylsulfanyl)-3-buten-2-ones with alkaline hydrogen peroxide in tetrahydrofuran. The stereochemistry of

Preparation and chemistry of phosphoranyl-derived iodanes

The preparation and chemistry of novel phosphoranyl-derived λ3-iodanes is reported. The phosphoranyl-derived phenyliodonium sulfonates were prepared in good yields by the reaction of stabilized phosphonium ylides [1-triphenylphosphoranylidene-2-propanone, methyl(triphenylphosphoranylidene)acetate, (triphenylphosphoranylidene)acetaldehyde, and (triphenylphosphoranylidene)acetonitrile] with the pyridinium complex of iodobenzene ditriflate or with [hydroxy(tosyloxy)-iodo]benzene under mild conditions. These compounds represent a potentially useful class of reagents that combine in one molecule synthetic advantages of a phosphonium ylide and an iodonium salt. Specifically, phosphorane-derived phenyliodonium tosylates can react with soft nucleophiles, such as iodide, bromide, benzenesulfinate, and thiophenolate anions, with a selective formation of the respective α-functionalized phosphonium ylides, which can be further converted to alkenes by the Wittig reaction with benzaldehyde. The phosphoranyl-derived benziodoxoles can be prepared by the reaction of 1-acetoxybenziodoxole with stabilized phosphonium ylides. An unusual ligand exchange on the iodine(III) center resulting in the substitution of a carbon ligand with an oxygen ligand was observed in the reaction of these compounds with strong acids.

Synthesis of α-phenylthioacylmethylene triphenylarsoranes and their Wittig-type reactions

α-Phenylthio acylmethylene triphenylarsoranes, the first stable α- thiyl arsonium ylides, are prepared by phenylsulfenylation-transylidation reaction of the corresponding acylmethylene triphenylarsoranes with phenylsulfenyl chloride; Wittig reactions are

Enantioselective synthesis of α-hydroxy thioesters via oxazaborolidine- mediated reduction of α-phenylthio enones

α-Phenylthio-α,β-alkenones (2), readily available by Pd(II)-catalysed coupling of (E)-1 phenylthio-1-tributylstannylhex-1-ene with the corresponding acid chlorides have been treated with borane in the presence of phenylglycine- or proline-derived oxazaborolidines to afford 2-phenylthio-2- alken-1-ols (3) with good to excellent enantioselectivities. Ozonolysis of 3 provides a new and efficient route to chiral α-hydroxy thioesters 4.

De-novo Synthesis of Carbohydrates and Related Natural Products, 18. - Hetero-Diels-Alder Reactions for the Synthesis of 3,4-Dihydro-2H-pyrans

Hetero-Diels-Alder reactions between α,β-unsaturated carbonyl compounds with functional substituents in α- and β-position and enol ethers, enediol ethers, and ketene acetals, respectively, result in the formation of 3,4-dihydro-2H-pyrans 3, having functio