143764-90-3

Upstream product

• 115851-28-0 5-[(4-chlorophenyl)methyl]-2,2-dimethylcyclopentanone 
• 1774-47-6 trimethylsulfoxonium iodide 
• 31608-26-1 2-(4-chlorobenzylidene)cyclopentanone 
• 120-92-3 cyclopentanone 
• 104-88-1 4-chlorobenzaldehyde 
• 131984-21-9 2,2-dimethyl-5-(4-chlorobenzylidene)cyclopentanone 
• 2181-42-2 trimethylsulphonium iodide 
• 3084-53-5 trimethylsulphonium bromide 

Downstream Products

• 125116-23-6 metconazole 
• 1370035-65-6 E-5-[1-(4-chlorobenzyliden)-1-hydroxymethyl-2, 2-dimethyl-cyclopentanol] 
• 143764-89-0 [2-(4-chloro-benzyl)-5,5-dimethyl-cyclopent-1-enyl]-methanol 

Relevant academic research and scientific papers

Method for synthesizing Metconazole epoxidation intermediate

The invention discloses a method for synthesizing a Metconazole epoxidation intermediate. The method comprises the steps: performing a reaction on trimethylsulfur halide or trimethyl sulfoxide halideand alkaline in a corresponding solvent under the condition of a catalyst so as to produce sulfur ylide, then adding 2,2-dimethyl-5-(4-chlorobenzyl)cyclopentanone, performing a Corey-Chaykovsky reaction, adding water and ethyl acetate for extraction after completion of the reaction, evaporating the organic phase until dryness, and recrystallizing the crude product so as to obtain the Meconazole epoxidation intermediate. According to the method for synthesizing the Metconazole epoxidation intermediate, epoxidation of carbonyl groups on cyclopentanone in the raw materials is performed through adoption of a catalyst for the Corey-Chaykovsky reaction and selection of a suitable solvent so as to achieve a satisfactory implementation effect, the epoxidation reaction time is shortened significantly, the conversion rate is improved, and the catalyst is cheap and easily available; and the method is suitable for industrial production.

[...] and its preparation method (by machine translation)

The invention discloses a high-purity [...] and its preparation method; its preparation as follows: cyclopentanone and P-formaldehyde condensation reaction to obtain the exocyclic double bond of the α, β - unsaturated ketone (II); then and methylation reagent reaction to obtain the α ', α' - double-methyl substituted exocyclic double bond of the α, β - unsaturated ketone (III); then under the action of catalyst and hydrogen reduction of the double bond is obtained by reaction of 2, 2 - dimethyl - 5 - (4 - benzylic) cyclopentanone (IV); the reduction product (IV) generating Johnson - Corey - Chaykovsky reaction to obtain the epoxy propane compound (V); finally the epoxy propane compounds (V) and 1, 2, 4 - triazole reaction and after recrystallized to obtain high-purity [...] (I). Preparation method of this invention the raw material is cheap, short route, good selectivity, high total yield, good atom economy advantages, is extremely suitable for industrial production. (by machine translation)

Azole derivatives and agricultural and horticultural chemical composition containing the same

Disclosed herein are an azole derivative represented by the formula(I): STR1 wherein R1 and R2 respectively represent a (C1 -C5) alkyl group or a hydrogen atom; X represents a halogen atom, a (C1 -Cs