14381-08-9

Upstream product

• 150-30-1 Phenylalanine 
• 105838-14-0 tert-butyl N-tosyloxycarbamate 
• 870-46-2 t-butoxycarbonylhydrazine 
• 13673-95-5 (S)-methyl 2-hydroxy-3-phenylpropanoate 
• 130608-06-9 (S)-methyl 2-((p-nitrobenzene)sulfonyl)oxy 3-phenylpropanoate 
• 130608-09-2 (R)-2-(N'-tert-Butoxycarbonyl-hydrazino)-3-phenyl-propionic acid methyl ester 
• 506444-17-3 2-hydrazino-3-phenyl-propionic acid ethyl ester 
• 13303-10-1 tert-Butyl 4-nitrophenyl carbonate 

Downstream Products

• 16257-28-6 N^β-tert.-Butyloxycarbonyl-DL-α-hydrazino-β-phenyl-propionsaeure-(p-nitro-phenylester) 
• 16257-29-7 N^β-tert.-Butyloxycarbonyl-DL-α-hydrazino-β-phenyl-propionsaeure-(2.4.5-trichlor-phenylester) 

Relevant academic research and scientific papers

N-amination of amino acids and its derivatives using N-Boc-O-tosyl hydroxylamine as an efficient NH-Boc transfer reagent: Electrophilic amination

Terminal tert-butyloxycarbonyl (Boc) protected hydrazino acids, useful intermediates for modified peptides and biologically active heterocyclic derivatives, were synthesized by electrophilic amination methodology using N-Boc-O-tosyl hydroxylamine as an ef

THE PREPARATION OF 2-HYDRAZINYL ESTERS IN HIGH OPTICAL PURITY FROM 2-SULFONYLOXY ESTERS

Chiral 2-triflyloxy esters, prepared from chiral 2-hydroxy esters, react enantiospecifically with BocNHNH2 to produce optically pure 2-hydrazinyl ester derivatives in high yields.The reaction of 2-nosyloxy esters with BocNHNH2 gives 2-(Boc-hydrazinyl) esters, thus providing an efficient (albeit slow) method for the conversion of esters to 2-hydrazinyl ester derivatives.