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(E)-N-(7-chloro-1-ethylquinolin-4(1H)-ylidene)-4-(4-(trifluoromethoxy)phenoxy)aniline trifluoromethanesulfonate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1438233-95-4

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1438233-95-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1438233-95-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,8,2,3 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1438233-95:
(9*1)+(8*4)+(7*3)+(6*8)+(5*2)+(4*3)+(3*3)+(2*9)+(1*5)=164
164 % 10 = 4
So 1438233-95-4 is a valid CAS Registry Number.

1438233-95-4Downstream Products

1438233-95-4Relevant academic research and scientific papers

Quinolin-4(1 H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria

Rodrigues, Tiago,Da Cruz, Filipa P.,Lafuente-Monasterio, Maria J.,Gon?alves, Daniel,Ressurrei??o, Ana S.,Sitoe, Ana R.,Bronze, Maria R.,Gut, Jiri,Schneider, Gisbert,Mota, Maria M.,Rosenthal, Philip J.,Prude?ncio, Miguel,Gamo, Francisco-Javier,Lopes, Francisca,Moreira, Rui

, p. 4811 - 4815 (2013/07/19)

We present a novel series of quinolin-4(1H)-imines as dual-stage antiplasmodials, several-fold more active than primaquine in vitro against Plasmodium berghei liver stage. Among those, compounds 5g and 5k presented low nanomolar IC50 values. The compounds are metabolically stable and modulate several drug targets. These results emphasize the value of quinolin-4(1H)-imines as a new chemotype and their suitable properties for further drug development.

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