143868-68-2Relevant academic research and scientific papers
Changes in Conformation and Antimicrobial Properties Caused by Replacement of D-Amino Acids with α-Aminoisobutyric Acid in the Gramicidin Backbone: Synthesis and Circular Dichroic Studies
Jelokhani-Niaraki, Masood,Yoshioka, Katsumi,Takahashi, Hiroki,Kato, Fumio,Kondo, Michio
, p. 1187 - 1193 (2007/10/02)
In an attempt to mimic the stable helical structures of proteins with possible pore-forming ability in membranes, the linear gramicidin backbone has been changed by inserting achiral α-aminoisobutyric acids (Aib) in place of all of the alternatively seque
