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14389-06-1

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14389-06-1 Usage

General Description

5-CHLORO-7-METHYLISATIN, also known as isatin 5-chloroacetate or 5-chloro-7-methylisatin, is an organic compound with a molecular formula of C9H6ClNO2. It is a derivative of isatin, a natural occurring compound found in plants and animal tissues. 5-CHLORO-7-METHYLISATIN is a pale yellow crystalline solid that is used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It exhibits a wide range of biological activities, including antimicrobial, antiviral, anticancer, and anti-inflammatory properties. 5-CHLORO-7-METHYLISATIN has potential applications in the development of new drugs and agrochemicals due to its diverse pharmacological profile and synthetic versatility.

Check Digit Verification of cas no

The CAS Registry Mumber 14389-06-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,8 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 14389-06:
(7*1)+(6*4)+(5*3)+(4*8)+(3*9)+(2*0)+(1*6)=111
111 % 10 = 1
So 14389-06-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H6ClNO2/c1-4-2-5(10)3-6-7(4)11-9(13)8(6)12/h2-3H,1H3,(H,11,12,13)

14389-06-1 Well-known Company Product Price

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  • Alfa Aesar

  • (L11682)  5-Chloro-7-methylisatin, 97%   

  • 14389-06-1

  • 250mg

  • 362.0CNY

  • Detail
  • Alfa Aesar

  • (L11682)  5-Chloro-7-methylisatin, 97%   

  • 14389-06-1

  • 1g

  • 1208.0CNY

  • Detail
  • Alfa Aesar

  • (L11682)  5-Chloro-7-methylisatin, 97%   

  • 14389-06-1

  • 5g

  • 4847.0CNY

  • Detail

14389-06-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Chloro-7-methylindoline-2,3-dione

1.2 Other means of identification

Product number -
Other names 5-Chloro-7-methylisatin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14389-06-1 SDS

14389-06-1Relevant articles and documents

AN EFFICIENT NEW PROCESS FOR SYNTHESIS OF 2-AMINO-5-CHLORO-N-,3-DIMETHYLBENZAMIDE

-

, (2021/05/07)

Described herein are novel methods of synthesizing 2-amino-5-chloro-N,3- dimethylbenzamide. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticides chlorantraniliprole and cyantraniliprole.

Preparation method of 2-amino-3-methyl-5-chlorobenzoic acid

-

Paragraph 0082-0083, (2021/05/12)

The invention belongs to the technical field of organic synthesis, and particularly relates to a preparation method of 2-amino-3-methyl-5-chlorobenzoic acid. The preparation method provided by the invention comprises the steps of mixing m-toluic acid and nitric acid, and carrying out nitration reaction to obtain 2-nitro-3-methyl benzoic acid, wherein the mass concentration of the nitric acid is 60-75%; mixing the 2-nitro-3-methyl benzoic acid, a hydrogenation reduction reaction solvent and a hydrogenation catalyst, and carrying out hydrogenation reduction reaction in a hydrogen atmosphere to obtain 2-amino-3-methyl benzoic acid; and mixing the 2-amino-3-methyl benzoic acid, a chlorination reagent, benzoyl peroxide and a chlorination reaction solvent, and carrying out a chlorination reaction to obtain the 2-amino-3-methyl-5-chlorobenzoic acid. The preparation method provided by the invention has the advantages of cheap and easily available reaction raw materials, high product yield and high purity, and is easy for industrial production.

Quinoline-3-carbothioamides and related compounds as novel immunomodulating agents

Tojo, Takashi,Spears, Glen W,Tsuji, Kiyoshi,Nishimura, Hiroaki,Ogino, Takashi,Seki, Nobuo,Sugiyama, Aiko,Matsuo, Masaaki

, p. 2427 - 2430 (2007/10/03)

A series of quinoline-3-carbothioamides and their analogues was prepared via four synthetic routes and evaluated for their antinephritic and immunomodulating activities. The optimal compound 9g strongly inhibited the T-cell independent antibody production in mice immunized with TNP-LPS and was highly effective in two nephritis models, namely chronic graft-versus-host disease and autoimmune MRL/l mice.

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