13208-93-0

Basic information

• Product Name: N1-(4-CHLORO-2-METHYLPHENYL)-2-HYDROXYIMINOACETAMIDE
• Synonyms: N1-(4-CHLORO-2-METHYLPHENYL)-2-HYDROXYIMINOACETAMIDE;ALPHA-ISONITROSO-4-CHLORO-2-METHYLACETANILIDE;N-(4-Chloro-2-Methylphenyl)-2-(hydroxyiMino)acetaMide
• CAS NO: 13208-93-0
• Molecular Formula: C₉H₉ClN₂O₂
• Molecular Weight: 212.63296
• Mol File: 13208-93-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 154-157 °C (decomp)
• Appearance: /
• Density: 1.31±0.1 g/cm3(Predicted)
• PKA: 8.69±0.10(Predicted)
• CAS DataBase Reference: N1-(4-CHLORO-2-METHYLPHENYL)-2-HYDROXYIMINOACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N1-(4-CHLORO-2-METHYLPHENYL)-2-HYDROXYIMINOACETAMIDE(13208-93-0)
• EPA Substance Registry System: N1-(4-CHLORO-2-METHYLPHENYL)-2-HYDROXYIMINOACETAMIDE(13208-93-0)

Safety Data

• Hazardous Substances Data: 13208-93-0(Hazardous Substances Data)

Upstream product

• 302-17-0 chloral hydrate 
• 95-69-2 4-chloro-2-methylbenzeneamine 
• 37394-93-7 2-chloro-N-(2-methylphenyl)acetamide 
• 1132-03-2 2-(hydroxyimino)-N-(2-methylphenyl)acetamide 

Downstream Products

• 14389-06-1 5-chloro-7-methyl-1H-indole-2,3-dione 

Relevant articles and documents

A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF

The present invention discloses a process for the synthesis of compound of formula (VII) or a salt thereof, wherein, R, R1, R2, R3, R4a and R4b are as defined in the detailed description. The process further comprises the synthesis of an anthranilic diamide compound of formula (I).

Quinoline-3-carbothioamides and related compounds as novel immunomodulating agents

A series of quinoline-3-carbothioamides and their analogues was prepared via four synthetic routes and evaluated for their antinephritic and immunomodulating activities. The optimal compound 9g strongly inhibited the T-cell independent antibody production in mice immunized with TNP-LPS and was highly effective in two nephritis models, namely chronic graft-versus-host disease and autoimmune MRL/l mice.